Optimization of In Vivo Studies by Combining Planar Dynamic and Tomographic Imaging: Workflow Evaluation on a Superparamagnetic Nanoparticles System.
Journal
Molecular imaging
ISSN: 1536-0121
Titre abrégé: Mol Imaging
Pays: England
ID NLM: 101120118
Informations de publication
Date de publication:
2021
2021
Historique:
received:
26
10
2020
accepted:
16
12
2020
entrez:
22
3
2021
pubmed:
23
3
2021
medline:
29
10
2021
Statut:
epublish
Résumé
Molecular imaging holds great promise in the noninvasive monitoring of several diseases with nanoparticles (NPs) being considered an efficient imaging tool for cancer, central nervous system, and heart- or bone-related diseases and for disorders of the mononuclear phagocytic system (MPS). In the present study, we used an iron-based nanoformulation, already established as an MRI/SPECT probe, as well as to load different biomolecules, to investigate its potential for nuclear planar and tomographic imaging of several target tissues following its distribution via different administration routes. Iron-doped hydroxyapatite NPs (FeHA) were radiolabeled with the single photon
Identifiants
pubmed: 33746630
doi: 10.1155/2021/6677847
pmc: PMC7953590
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
6677847Informations de copyright
Copyright © 2021 Maritina Rouchota et al.
Déclaration de conflit d'intérêts
The authors have no conflict of interest to declare.
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