Synthesis and properties of oligonucleotides modified with an

artificial nucleic acid duplex-forming ability oligonucleotide synthesis

Journal

Beilstein journal of organic chemistry
ISSN: 1860-5397
Titre abrégé: Beilstein J Org Chem
Pays: Germany
ID NLM: 101250746

Informations de publication

Date de publication:
2021
Historique:
received: 06 11 2020
accepted: 18 02 2021
entrez: 22 3 2021
pubmed: 23 3 2021
medline: 23 3 2021
Statut: epublish

Résumé

Chemical modifications have been extensively used for therapeutic oligonucleotides because they strongly enhance the stability against nucleases, binding affinity to the targets, and efficacy. We previously reported that oligonucleotides modified with an

Identifiants

pubmed: 33747234
doi: 10.3762/bjoc.17.54
pmc: PMC7940814
doi:

Types de publication

Journal Article

Langues

eng

Pagination

622-629

Informations de copyright

Copyright © 2021, Horie et al.

Références

Chem Commun (Camb). 2014 Jan 18;50(5):575-7
pubmed: 24270219
Nucleic Acids Res. 2014 Jul;42(12):8174-87
pubmed: 24935206
Org Biomol Chem. 2015 Mar 28;13(12):3757-65
pubmed: 25690587
Org Lett. 2004 Jun 10;6(12):1971-4
pubmed: 15176796
Mol Ther Nucleic Acids. 2018 Jun 1;11:441-454
pubmed: 29858079
Leukemia. 2018 Sep;32(9):1948-1957
pubmed: 29487387
Org Biomol Chem. 2020 Dec 7;18(46):9461-9472
pubmed: 33179694
Chem Rev. 2007 Nov;107(11):4672-97
pubmed: 17944519
Org Biomol Chem. 2018 Sep 11;16(35):6531-6536
pubmed: 30160290
Org Biomol Chem. 2011 Jan 7;9(1):243-52
pubmed: 21049102
Clin Cancer Res. 2019 Dec 1;25(23):7189-7201
pubmed: 31530630
Nucleic Acid Ther. 2018 Oct;28(5):273-284
pubmed: 30133337
J Pharmacol Exp Ther. 2015 Nov;355(2):329-40
pubmed: 26330536
Bioorg Med Chem. 2019 Apr 15;27(8):1728-1741
pubmed: 30862430
J Org Chem. 2016 Nov 18;81(22):11000-11008
pubmed: 27779877
Mol Ther. 2011 Dec;19(12):2178-85
pubmed: 21971427
Bioorg Med Chem. 2012 Feb 15;20(4):1594-606
pubmed: 22264759
Chembiochem. 2006 Apr;7(4):684-92
pubmed: 16518865
Org Lett. 2018 Apr 6;20(7):1928-1931
pubmed: 29528240
J Med Chem. 2009 Jan 8;52(1):10-3
pubmed: 19086780
Nucleic Acids Res. 2009 Mar;37(4):1225-38
pubmed: 19136459
Nucleic Acids Symp Ser (Oxf). 2008;(52):553-4
pubmed: 18776499
Molecules. 2017 May 21;22(5):
pubmed: 28531137
J Org Chem. 2010 Mar 5;75(5):1569-81
pubmed: 20136157

Auteurs

Naohiro Horie (N)

Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.

Takao Yamaguchi (T)

Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.

Shinji Kumagai (S)

Sohyaku. Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Shonan Health Innovation Park, 2-26-1 Muraoka-Higashi, Fujisawa, Kanagawa 251-8555, Japan.

Satoshi Obika (S)

Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.
National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), 7-6-8 Saito-Asagi, Ibaraki, Osaka 567-0085, Japan.

Classifications MeSH