Establishment of a standardized dietary model for nanoparticles oral exposure studies.
food matrixes
nanoparticles
stability
standardized dietary model
Journal
Food science & nutrition
ISSN: 2048-7177
Titre abrégé: Food Sci Nutr
Pays: United States
ID NLM: 101605473
Informations de publication
Date de publication:
Mar 2021
Mar 2021
Historique:
received:
31
07
2020
revised:
27
11
2020
accepted:
26
12
2020
entrez:
22
3
2021
pubmed:
23
3
2021
medline:
23
3
2021
Statut:
epublish
Résumé
Food matrices could affect the physicochemical properties of nanoparticles (NPs) and define the biological effects of NPs via oral exposure compared with the pristine NPs. We established a standardized dietary model based on Chinese dietary reference intakes and Chinese dietary guidelines to mimic the exposure of NPs in real life and to evaluate further the biological effect and toxicity of NPs via oral exposure compared with current models. The standardized dietary model prepared from the primary emulsion was dried into powder using spray drying compared with commercial food powder and then was reconstituted compared with the fresh sample. The average particle size (295.59 nm), potential (-23.78 mV), viscosity (0.04 pa s), and colors (L
Identifiants
pubmed: 33747458
doi: 10.1002/fsn3.2112
pii: FSN32112
pmc: PMC7958543
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1441-1451Informations de copyright
© 2021 The Authors. Food Science & Nutrition published by Wiley Periodicals LLC.
Déclaration de conflit d'intérêts
The authors declare that they have no conflict of interest.
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