Dilation of Brain Veins and Perivascular Infiltration by Glioblastoma Cells in an
Journal
BioMed research international
ISSN: 2314-6141
Titre abrégé: Biomed Res Int
Pays: United States
ID NLM: 101600173
Informations de publication
Date de publication:
2021
2021
Historique:
received:
10
09
2020
revised:
22
02
2021
accepted:
27
02
2021
entrez:
22
3
2021
pubmed:
23
3
2021
medline:
26
5
2021
Statut:
epublish
Résumé
The cranial window (CW) technique provides a simple and low-cost method to assess tumor angiogenesis in the brain. The CW combined with histology using selective markers for tumor and endothelial cells can allow a sensitive monitoring of novel antiangiogenesis therapies in preclinical models. The CW was established in cyclosporine immunosuppressed rats that were stereotactically grafted with fluorescent U87MG glioblastoma cells. One to 3 weeks after grafting, brain vasculature was visualized
Identifiants
pubmed: 33748283
doi: 10.1155/2021/8891045
pmc: PMC7960033
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
8891045Informations de copyright
Copyright © 2021 Quintino Giorgio D'Alessandris et al.
Déclaration de conflit d'intérêts
The authors declare that there is no conflict of interest regarding the publication of this paper.
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