Dual regulation of TxNIP by ChREBP and FoxO1 in liver.
Endocrinology
Molecular Biology
Molecular Physiology
Journal
iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038
Informations de publication
Date de publication:
19 Mar 2021
19 Mar 2021
Historique:
received:
02
03
2020
revised:
17
11
2020
accepted:
18
02
2021
entrez:
22
3
2021
pubmed:
23
3
2021
medline:
23
3
2021
Statut:
epublish
Résumé
TxNIP (Thioredoxin-interacting protein) is considered as a potential drug target for type 2 diabetes. Although TxNIP expression is correlated with hyperglycemia and glucotoxicity in pancreatic β cells, its regulation in liver cells has been less investigated. In the current study, we aim at providing a better understanding of
Identifiants
pubmed: 33748706
doi: 10.1016/j.isci.2021.102218
pii: S2589-0042(21)00186-3
pmc: PMC7966993
doi:
Types de publication
Journal Article
Langues
eng
Pagination
102218Informations de copyright
© 2021.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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