Postoperative outcomes, lymph node dissection and effects on costs among thoracotomy, video-assisted and robotic-assisted lobectomy for clinical stage I non-small cell lung cancer.


Journal

Minerva surgery
ISSN: 2724-5438
Titre abrégé: Minerva Surg
Pays: Italy
ID NLM: 101777295

Informations de publication

Date de publication:
Feb 2021
Historique:
entrez: 23 3 2021
pubmed: 24 3 2021
medline: 29 10 2021
Statut: ppublish

Résumé

Thoracotomy, video-assisted thoracoscopic surgery (VATS) and robotic assisted thoracoscopic surgery (RATS)-lobectomy are widely accepted procedures for the surgical treatment of clinical (c)stage I non- small cell lung cancer (NSCLC). In the current literature which procedure gives more benefits is still debated. We present a comparison between these three procedures in term of advantages and postoperative outcomes. A multicentric study about 259 lobectomies from 2013 to 2019: 128 patients underwent TL, 96 VATS and 35 RATS. Different variables were retrospectively analyzed among these three cohorts of patients with diagnosis of cStage I NSCLC. Rate of major complications comparable in VATS, RATS and TL; Advantages for RATS in minor complications (TL 34.4% vs. VATS 18.75% vs. RATS 8.57%. P=0.0015), postoperative days in Intensive Care Unit, days to chest tube removal, length of postoperative hospitalization (P<0.0001) and number of lymph nodes dissected (P=0.0257). Operating times are shorter in VATS than RATS (P<0.05). Pain (NRS Scale) is comparable. TL remains the conventional approach for stage II-IIIA(N2) NSCLC. RATS showed great advantages, but its higher operating time and costs, mostly, today don't justify its adoption as gold standard for the surgical treatment of cStage I NSCLC, instead of VATS.

Sections du résumé

BACKGROUND BACKGROUND
Thoracotomy, video-assisted thoracoscopic surgery (VATS) and robotic assisted thoracoscopic surgery (RATS)-lobectomy are widely accepted procedures for the surgical treatment of clinical (c)stage I non- small cell lung cancer (NSCLC). In the current literature which procedure gives more benefits is still debated. We present a comparison between these three procedures in term of advantages and postoperative outcomes.
METHODS METHODS
A multicentric study about 259 lobectomies from 2013 to 2019: 128 patients underwent TL, 96 VATS and 35 RATS. Different variables were retrospectively analyzed among these three cohorts of patients with diagnosis of cStage I NSCLC.
RESULTS RESULTS
Rate of major complications comparable in VATS, RATS and TL; Advantages for RATS in minor complications (TL 34.4% vs. VATS 18.75% vs. RATS 8.57%. P=0.0015), postoperative days in Intensive Care Unit, days to chest tube removal, length of postoperative hospitalization (P<0.0001) and number of lymph nodes dissected (P=0.0257). Operating times are shorter in VATS than RATS (P<0.05). Pain (NRS Scale) is comparable.
CONCLUSIONS CONCLUSIONS
TL remains the conventional approach for stage II-IIIA(N2) NSCLC. RATS showed great advantages, but its higher operating time and costs, mostly, today don't justify its adoption as gold standard for the surgical treatment of cStage I NSCLC, instead of VATS.

Identifiants

pubmed: 33754591
pii: S2724-5691.20.08395-9
doi: 10.23736/S2724-5691.20.08395-9
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

80-89

Auteurs

Roberto Gullo (R)

Department of Thoracic Surgery, Paolo Giaccone University Hospital, Palermo, Italy.

Carola M Gagliardo (CM)

Department of Surgical, Oncological and Stomatological Sciences, Paolo Giaccone University Hospital, Palermo, Italy - carola.gagliardo@libero.it.

Manuela Palazzolo (M)

Department of Thoracic Surgery, Paolo Giaccone University Hospital, Palermo, Italy.

Calogero Porrello (C)

Department of Thoracic Surgery, Paolo Giaccone University Hospital, Palermo, Italy.

Leonardo Gulotta (L)

Department of General and Oncologic Surgery, Gaetano Martino University Hospital, Messina, Italy.

Felice Lo Faso (F)

Department of Thoracic Surgery, Azienda Ospedaliera Ospedali Riuniti Marche Nord, Pesaro, Italy.

Gaspare Gulotta (G)

Department of General and Emergency Surgery, Paolo Giaccone University Hospital, Palermo, Italy.

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