Test conditions can significantly affect the results of in vitro cytotoxicity testing of degradable metallic biomaterials.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
23 03 2021
23 03 2021
Historique:
received:
20
11
2020
accepted:
12
02
2021
entrez:
24
3
2021
pubmed:
25
3
2021
medline:
25
2
2023
Statut:
epublish
Résumé
In vitro cytotoxicity testing is an indispensable part of the development of new biomaterials. However, the standard ISO 10993-5 enables variability in the testing conditions, which makes the results of the test incomparable. We studied the influence of media composition on the results of the cytotoxicity test. Solutions of ZnCl
Identifiants
pubmed: 33758226
doi: 10.1038/s41598-021-85019-6
pii: 10.1038/s41598-021-85019-6
pmc: PMC7987994
doi:
Substances chimiques
Alloys
0
Biocompatible Materials
0
Coordination Complexes
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
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