Sarcopenic obesity and function in women with subacute hip fracture: a short-term prospective study.


Journal

European journal of physical and rehabilitation medicine
ISSN: 1973-9095
Titre abrégé: Eur J Phys Rehabil Med
Pays: Italy
ID NLM: 101465662

Informations de publication

Date de publication:
Dec 2021
Historique:
pubmed: 25 3 2021
medline: 24 12 2021
entrez: 24 3 2021
Statut: ppublish

Résumé

The prognostic role exerted by the concurrent presence of sarcopenia and obesity after hip fracture has not been elucidated. To assess the effect of sarcopenic obesity on ability to function in women with subacute hip fracture. Short-term prospective study. Rehabilitation hospital. Women with subacute hip fracture. At admission, grip strength, by a Jamar dynamometer, and body composition by dual-energy x-ray absorptiometry were assessed. Sarcopenia was defined according to the criteria released by the European Working Group for Sarcopenia in Older People in 2019, with both grip strength <16 kg and appendicular lean mass (aLM)<15 kg. Alternatively, aLM/(height) We assessed 183 of 200 women. Sarcopenic women had lower Barthel index scores assessed at the end of subacute inpatient rehabilitation (U=300,0; z=-4.3; P<0.001) and lower Batrhel index effectiveness (U=310,0; z=-4.2; P<0.001) than non-sarcopenic women. Conversely, we found no significant differences in function between obese and non-obese women. The concurrent presence of sarcopenia and obesity did not worsen the functional prognosis versus the presence of isolated sarcopenia. After adjustment for Barthel index scores before rehabilitation, age, hip-fracture type and cognitive impairment, sarcopenia was significantly associated with Barthel index scores (P=0.001) and Barthel index effectiveness (P<0.001), whereas obesity was not. The results did not materially change when aLM/(height)2<5.5 kg/m2 was substituted for aLM <15 kg to confirm sarcopenia in the women whose handgrip strength was <16 kg. The concurrent presence of obesity did not worsen the negative prognostic role of sarcopenia in the short-term recovery of ability to function after hip fracture in women. In women with subacute hip fracture, sarcopenia but not obesity should be assessed to contribute to the prediction of the short-term functional outcome.

Sections du résumé

BACKGROUND BACKGROUND
The prognostic role exerted by the concurrent presence of sarcopenia and obesity after hip fracture has not been elucidated.
AIM OBJECTIVE
To assess the effect of sarcopenic obesity on ability to function in women with subacute hip fracture.
DESIGN METHODS
Short-term prospective study.
SETTING METHODS
Rehabilitation hospital.
POPULATION METHODS
Women with subacute hip fracture.
METHODS METHODS
At admission, grip strength, by a Jamar dynamometer, and body composition by dual-energy x-ray absorptiometry were assessed. Sarcopenia was defined according to the criteria released by the European Working Group for Sarcopenia in Older People in 2019, with both grip strength <16 kg and appendicular lean mass (aLM)<15 kg. Alternatively, aLM/(height)
RESULTS RESULTS
We assessed 183 of 200 women. Sarcopenic women had lower Barthel index scores assessed at the end of subacute inpatient rehabilitation (U=300,0; z=-4.3; P<0.001) and lower Batrhel index effectiveness (U=310,0; z=-4.2; P<0.001) than non-sarcopenic women. Conversely, we found no significant differences in function between obese and non-obese women. The concurrent presence of sarcopenia and obesity did not worsen the functional prognosis versus the presence of isolated sarcopenia. After adjustment for Barthel index scores before rehabilitation, age, hip-fracture type and cognitive impairment, sarcopenia was significantly associated with Barthel index scores (P=0.001) and Barthel index effectiveness (P<0.001), whereas obesity was not. The results did not materially change when aLM/(height)2<5.5 kg/m2 was substituted for aLM <15 kg to confirm sarcopenia in the women whose handgrip strength was <16 kg.
CONCLUSIONS CONCLUSIONS
The concurrent presence of obesity did not worsen the negative prognostic role of sarcopenia in the short-term recovery of ability to function after hip fracture in women.
CLINICAL REHABILITATION IMPACT CONCLUSIONS
In women with subacute hip fracture, sarcopenia but not obesity should be assessed to contribute to the prediction of the short-term functional outcome.

Identifiants

pubmed: 33759440
pii: S1973-9087.21.06720-4
doi: 10.23736/S1973-9087.21.06720-4
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

940-947

Auteurs

Marco DI Monaco (M)

Division of Physical and Rehabilitation Medicine, Osteoporosis Research Center, Presidio Sanitario San Camillo, Opera San Camillo Foundation, Turin, Italy - marco.di.monaco@alice.it.
- marco.di.monaco@alice.it.

Carlotta Castiglioni (C)

Division of Physical and Rehabilitation Medicine, Osteoporosis Research Center, Presidio Sanitario San Camillo, Opera San Camillo Foundation, Turin, Italy.

Francesca Bardesono (F)

Division of Physical and Rehabilitation Medicine, Department of Surgical Sciences, University of Turin, Turin, Italy.

Edoardo Milano (E)

Division of Physical and Rehabilitation Medicine, Osteoporosis Research Center, Presidio Sanitario San Camillo, Opera San Camillo Foundation, Turin, Italy.

Giuseppe Massazza (G)

Division of Physical and Rehabilitation Medicine, Department of Surgical Sciences, University of Turin, Turin, Italy.

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