REV-ERB in GABAergic neurons controls diurnal hepatic insulin sensitivity.

Animals Blood Glucose Circadian Clocks Circadian Rhythm Diabetes Mellitus, Type 2 Female GABAergic Neurons / physiology Glucose / metabolism Humans Insulin Resistance Liver / physiology Male Mice Mice, Inbred C57BL Mice, Knockout Middle Aged Nuclear Receptor Subfamily 1, Group D, Member 1 / physiology Photoperiod Suprachiasmatic Nucleus / cytology Synaptic Transmission

Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
04 2021
Historique:
received: 17 06 2020
accepted: 12 02 2021
pubmed: 26 3 2021
medline: 11 1 2022
entrez: 25 3 2021
Statut: ppublish

Résumé

Systemic insulin sensitivity shows a diurnal rhythm with a peak upon waking

Identifiants

DOI: 10.1038/s41586-021-03358-w PMID: 33762728 PMC: PMC8085086
pubmed: 33762728
doi: 10.1038/s41586-021-03358-w
pii: 10.1038/s41586-021-03358-w
pmc: PMC8085086
mid: NIHMS1673610
doi:

Substances chimiques

Blood Glucose 0
Nuclear Receptor Subfamily 1, Group D, Member 1 0
Glucose IY9XDZ35W2

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

763-767

Subventions

Organisme : NIH HHS
ID : S10 OD016167
Pays : United States
Organisme : NIA NIH HHS
ID : R03 AG070687
Pays : United States
Organisme : NICHD NIH HHS
ID : U54 HD083092
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK056338
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK111436
Pays : United States
Organisme : NIGMS NIH HHS
ID : P20 GM135002
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK114356
Pays : United States
Organisme : NIDDK NIH HHS
ID : R00 DK099443
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL153320
Pays : United States
Organisme : NCI NIH HHS
ID : R21 CA215591
Pays : United States
Organisme : NIA NIH HHS
ID : RF1 AG069966
Pays : United States
Organisme : NCI NIH HHS
ID : P50 CA126752
Pays : United States
Organisme : NIEHS NIH HHS
ID : P30 ES030285
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA125123
Pays : United States
Organisme : NHGRI NIH HHS
ID : UM1 HG006348
Pays : United States
Organisme : NICHD NIH HHS
ID : P50 HD103555
Pays : United States
Organisme : NIEHS NIH HHS
ID : R01 ES027544
Pays : United States

Commentaires et corrections

Type : ErratumIn

Références

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Auteurs

Guolian Ding (G)

Obstetrics and Gynecology Hospital, Institute of Reproduction and Development, Fudan University, Shanghai, China.
Shanghai Key Laboratory of Embryo Original Diseases, Shanghai, China.
Department of Medicine, Division of Diabetes, Endocrinology and Metabolism, Baylor College of Medicine, Houston, TX, USA.

Xin Li (X)

Department of Medicine, Division of Diabetes, Endocrinology and Metabolism, Baylor College of Medicine, Houston, TX, USA.

Xinguo Hou (X)

Department of Endocrinology, Qilu Hospital of Shandong University, Jinan, China.
ORCID: 0000-0003-2045-1290

Wenjun Zhou (W)

Department of Medicine, Division of Diabetes, Endocrinology and Metabolism, Baylor College of Medicine, Houston, TX, USA.

Yingyun Gong (Y)

Department of Medicine, Division of Diabetes, Endocrinology and Metabolism, Baylor College of Medicine, Houston, TX, USA.
Department of Endocrinology and Metabolism, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
ORCID: 0000-0002-8570-6904

Fuqiang Liu (F)

Department of Endocrinology, Qilu Hospital of Shandong University, Jinan, China.

Yanlin He (Y)

USDA/ARS Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Laboratory of Brain Glycemia and Metabolism Control, Pennington Biomedical Research Center, Baton Rouge, LA, USA.
ORCID: 0000-0002-5471-9016

Jia Song (J)

Department of Endocrinology, Qilu Hospital of Shandong University, Jinan, China.

Jing Wang (J)

Department of Endocrinology, Qilu Hospital of Shandong University, Jinan, China.

Paul Basil (P)

Department of Medicine, Division of Diabetes, Endocrinology and Metabolism, Baylor College of Medicine, Houston, TX, USA.

Wenbo Li (W)

Department of Medicine, Division of Diabetes, Endocrinology and Metabolism, Baylor College of Medicine, Houston, TX, USA.
ORCID: 0000-0002-9126-2529

Sichong Qian (S)

Department of Medicine, Division of Diabetes, Endocrinology and Metabolism, Baylor College of Medicine, Houston, TX, USA.

Pradip Saha (P)

Department of Medicine, Division of Diabetes, Endocrinology and Metabolism, Baylor College of Medicine, Houston, TX, USA.
Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.

Jinbang Wang (J)

Department of Endocrinology, Qilu Hospital of Shandong University, Jinan, China.

Chen Cui (C)

Department of Endocrinology, Qilu Hospital of Shandong University, Jinan, China.

Tingting Yang (T)

Department of Medicine, Division of Diabetes, Endocrinology and Metabolism, Baylor College of Medicine, Houston, TX, USA.
USDA/ARS Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.

Kexin Zou (K)

Obstetrics and Gynecology Hospital, Institute of Reproduction and Development, Fudan University, Shanghai, China.
Shanghai Key Laboratory of Embryo Original Diseases, Shanghai, China.

Younghun Han (Y)

Department of Medicine, Section of Epidemiology and Population Sciences, Baylor College of Medicine, Houston, TX, USA.

Christopher I Amos (CI)

Department of Medicine, Section of Epidemiology and Population Sciences, Baylor College of Medicine, Houston, TX, USA.

Yong Xu (Y)

USDA/ARS Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.
ORCID: 0000-0002-4908-1572

Li Chen (L)

Department of Endocrinology, Qilu Hospital of Shandong University, Jinan, China. chenli3@medmail.com.cn.
ORCID: 0000-0001-7670-8062

Zheng Sun (Z)

Department of Medicine, Division of Diabetes, Endocrinology and Metabolism, Baylor College of Medicine, Houston, TX, USA. zheng.sun@bcm.edu.
Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA. zheng.sun@bcm.edu.
ORCID: 0000-0002-6858-0633

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › REV-ERB in GABAergic neurons controls diurnal...
questionsmedicales.fr › Glucides › Sucres › Oses › Hexose › Glucose › Glycémie › REV-ERB in GABAergic neurons controls diurnal...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes chronobiologiques › Périodicité › Horloges biologiques › Horloges circadiennes › REV-ERB in GABAergic neurons controls diurnal...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes chronobiologiques › Périodicité › Rythme circadien › REV-ERB in GABAergic neurons controls diurnal...
questionsmedicales.fr › Maladies endocriniennes › Diabète › Diabète de type 2 › REV-ERB in GABAergic neurons controls diurnal...
questionsmedicales.fr › Cellules › Neurones › Neurones GABAergiques › REV-ERB in GABAergic neurons controls diurnal...
questionsmedicales.fr › Glucides › Sucres › Oses › Hexose › Glucose › REV-ERB in GABAergic neurons controls diurnal...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › REV-ERB in GABAergic neurons controls diurnal...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Résistance aux substances › Insulinorésistance › REV-ERB in GABAergic neurons controls diurnal...
questionsmedicales.fr › Système digestif › Foie › REV-ERB in GABAergic neurons controls diurnal...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › REV-ERB in GABAergic neurons controls diurnal...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › REV-ERB in GABAergic neurons controls diurnal...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Souris knockout › REV-ERB in GABAergic neurons controls diurnal...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › REV-ERB in GABAergic neurons controls diurnal...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Récepteurs cytoplasmiques et nucléaires › Membre-1 du groupe D de la sous-famille-1 de récepteurs nucléaires › REV-ERB in GABAergic neurons controls diurnal...
questionsmedicales.fr › Phénomènes physiques › Temps › Photopériode › REV-ERB in GABAergic neurons controls diurnal...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Prosencéphale › Diencéphale › Hypothalamus › Hypothalamus antérieur › Noyau suprachiasmatique › REV-ERB in GABAergic neurons controls diurnal...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Transmission synaptique › REV-ERB in GABAergic neurons controls diurnal...