A multi-channel uncertainty-aware multi-resolution network for MR to CT synthesis.

MR to CT synthesis Multi-resolution CNN Uncertainty

Journal

Applied sciences (Basel, Switzerland)
ISSN: 2076-3417
Titre abrégé: Appl Sci (Basel)
Pays: Switzerland
ID NLM: 101633495

Informations de publication

Date de publication:
Feb 2021
Historique:
entrez: 25 3 2021
pubmed: 26 3 2021
medline: 26 3 2021
Statut: epublish

Résumé

Synthesising computed tomography (CT) images from magnetic resonance images (MRI) plays an important role in the field of medical image analysis, both for quantification and diagnostic purposes. Convolutional neural networks (CNNs) have achieved state-of-the-art results in image-to-image translation for brain applications. However, synthesising whole-body images remains largely uncharted territory involving many challenges, including large image size and limited field of view, complex spatial context, and anatomical differences between images acquired at different times. We propose the use of an uncertainty-aware multi-channel multi-resolution 3D cascade network specifically aiming for whole-body MR to CT synthesis. The Mean Absolute Error on the synthetic CT generated with the MultiRes

Identifiants

pubmed: 33763236
doi: 10.3390/app11041667
pmc: PMC7610395
mid: EMS117270
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1667

Subventions

Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 203148
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 213038
Pays : United Kingdom

Déclaration de conflit d'intérêts

Conflicts of Interest: The authors declare no conflict of interest.

Références

Med Image Anal. 2017 Feb;36:61-78
pubmed: 27865153
Comput Methods Programs Biomed. 2018 May;158:113-122
pubmed: 29544777
IEEE Trans Med Imaging. 2014 Dec;33(12):2332-41
pubmed: 25055381
Med Image Anal. 2020 Jan;59:101557
pubmed: 31677438
Comput Methods Programs Biomed. 2010 Jun;98(3):278-84
pubmed: 19818524
Neuroimage. 2017 Feb 15;147:346-359
pubmed: 27988322

Auteurs

Kerstin Kläser (K)

Dept. Medical Physics & Biomedical Engineering, University College London, UK.
School of Biomedical Engineering & Imaging Sciences, King's College London, UK.

Pedro Borges (P)

Dept. Medical Physics & Biomedical Engineering, University College London, UK.
School of Biomedical Engineering & Imaging Sciences, King's College London, UK.

Richard Shaw (R)

Dept. Medical Physics & Biomedical Engineering, University College London, UK.
School of Biomedical Engineering & Imaging Sciences, King's College London, UK.

Marta Ranzini (M)

Dept. Medical Physics & Biomedical Engineering, University College London, UK.
School of Biomedical Engineering & Imaging Sciences, King's College London, UK.

Marc Modat (M)

School of Biomedical Engineering & Imaging Sciences, King's College London, UK.

David Atkinson (D)

Centre for Medical Imaging, University College London, UK.

Kris Thielemans (K)

Institute of Nuclear Medicine, University College London, UK.

Brian Hutton (B)

Institute of Nuclear Medicine, University College London, UK.

Vicky Goh (V)

School of Biomedical Engineering & Imaging Sciences, King's College London, UK.

Gary Cook (G)

School of Biomedical Engineering & Imaging Sciences, King's College London, UK.

M Jorge Cardoso (MJ)

School of Biomedical Engineering & Imaging Sciences, King's College London, UK.

Sébastien Ourselin (S)

School of Biomedical Engineering & Imaging Sciences, King's College London, UK.

Classifications MeSH