Comparison of the multi-phasic longitudinal displacement of the left and right common carotid artery in healthy humans.
arterial wall
axial displacement
diameter change
longitudinal motion
ultrasound
Journal
Clinical physiology and functional imaging
ISSN: 1475-097X
Titre abrégé: Clin Physiol Funct Imaging
Pays: England
ID NLM: 101137604
Informations de publication
Date de publication:
Jul 2021
Jul 2021
Historique:
revised:
16
02
2021
received:
05
10
2020
accepted:
18
03
2021
pubmed:
26
3
2021
medline:
26
10
2021
entrez:
25
3
2021
Statut:
ppublish
Résumé
During the cardiac cycle, there is a multi-phasic bidirectional longitudinal movement (LMov) of the intima-media complex of large arteries, i.e. along the arteries. On the left side the common carotid artery (CCA) arises directly from the aortic arc, whereas on the right side the CCA originate from the innominate artery. The aim of this study was to compare LMov of the left and right CCA of healthy subjects to investigate whether the difference in anatomy is of importance for LMov. The CCA's of 93 healthy subjects were investigated using in-house developed ultrasound methods. Although the basic pattern were the same in the majority of subjects, several phases of LMov were significantly larger on the left side (the first retrograde phase, p = 0.0006; the second antegrade, "returning" phase, p < 0.00001; and the rapid retrograde phase of movement at the end of the cardiac cycle, p < 0.000001). In contrast, no significant side-difference in the amplitude of the first antegrade movement was seen. The maximal (peak-to-peak) LMov was significantly larger on the left side (p = 0.002). The side-differences found in LMov may be related to the difference in anatomy, including possible difference in distance to the heart and especially the presence of an extra bifurcation on the right side. Our data provide an important base for the further study of the relation between LMov and cardiovascular risk factors and atherosclerosis.
Sections du résumé
BACKGROUND
BACKGROUND
During the cardiac cycle, there is a multi-phasic bidirectional longitudinal movement (LMov) of the intima-media complex of large arteries, i.e. along the arteries. On the left side the common carotid artery (CCA) arises directly from the aortic arc, whereas on the right side the CCA originate from the innominate artery.
AIM
OBJECTIVE
The aim of this study was to compare LMov of the left and right CCA of healthy subjects to investigate whether the difference in anatomy is of importance for LMov.
MATERIAL AND METHODS
METHODS
The CCA's of 93 healthy subjects were investigated using in-house developed ultrasound methods.
RESULTS
RESULTS
Although the basic pattern were the same in the majority of subjects, several phases of LMov were significantly larger on the left side (the first retrograde phase, p = 0.0006; the second antegrade, "returning" phase, p < 0.00001; and the rapid retrograde phase of movement at the end of the cardiac cycle, p < 0.000001). In contrast, no significant side-difference in the amplitude of the first antegrade movement was seen. The maximal (peak-to-peak) LMov was significantly larger on the left side (p = 0.002).
DISCUSSION AND CONCLUSION
CONCLUSIONS
The side-differences found in LMov may be related to the difference in anatomy, including possible difference in distance to the heart and especially the presence of an extra bifurcation on the right side. Our data provide an important base for the further study of the relation between LMov and cardiovascular risk factors and atherosclerosis.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
342-354Subventions
Organisme : Heart Lung Foundation, Sweden
Organisme : The Medical Faculty; Lund University
Organisme : The Swedish Research Council
Organisme : The Skåne County Research Council
Organisme : Funds at Skåne University Hospital
Organisme : Region Östergötland
Organisme : Erasmus+ International Credit Mobility for incoming PhD students at Lund University
Informations de copyright
© 2021 The Authors. Clinical Physiology and Functional Imaging published by John Wiley & Sons Ltd on behalf of Scandinavian Society of Clinical Physiology and Nuclear Medicine.
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