Impact of COVID-19 on exercise pathophysiology: a combined cardiopulmonary and echocardiographic exercise study.


Journal

Journal of applied physiology (Bethesda, Md. : 1985)
ISSN: 1522-1601
Titre abrégé: J Appl Physiol (1985)
Pays: United States
ID NLM: 8502536

Informations de publication

Date de publication:
01 05 2021
Historique:
pubmed: 26 3 2021
medline: 24 6 2021
entrez: 25 3 2021
Statut: ppublish

Résumé

Survivors from COVID-19 pneumonia can present with persisting multisystem involvement (lung, pulmonary vessels, heart, muscle, red blood cells) that may negatively affect exercise capacity. We sought to determine the extent and the determinants of exercise limitation in patients with COVID-19 at the time of hospital discharge. Eighteen consecutive patients with COVID-19 and 1:1 age-, sex-, and body mass index-matched controls underwent: spirometry, echocardiography, cardiopulmonary exercise test and exercise echocardiography for the study of pulmonary circulation. Arterial blood was sampled at rest and during exercise in patients with COVID-19. Patients with COVID-19 lie roughly on the same oxygen consumption isophlets than controls both at rest and during submaximal exercise, thanks to supernormal cardiac output (

Identifiants

pubmed: 33764166
doi: 10.1152/japplphysiol.00710.2020
pmc: PMC8143785
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1470-1478

Subventions

Organisme : Italian Ministry of Health

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Auteurs

Claudia Baratto (C)

Department of Cardiovascular, Neural and Metabolic Sciences, Istituto Auxologico Italiano IRCCS, Ospedale San Luca, Milano, Italy.
Department of Medicine and Surgery, University of Milano-Bicocca, Milano, Italy.

Sergio Caravita (S)

Department of Cardiovascular, Neural and Metabolic Sciences, Istituto Auxologico Italiano IRCCS, Ospedale San Luca, Milano, Italy.
Department of Management, Information and Production Engineering, University of Bergamo, Dalmine, Italy.

Andrea Faini (A)

Department of Cardiovascular, Neural and Metabolic Sciences, Istituto Auxologico Italiano IRCCS, Ospedale San Luca, Milano, Italy.

Giovanni Battista Perego (GB)

Department of Cardiovascular, Neural and Metabolic Sciences, Istituto Auxologico Italiano IRCCS, Ospedale San Luca, Milano, Italy.

Michele Senni (M)

Cardiovascular Department, ASST Papa Giovanni XXIII, Bergamo, Italy.

Luigi P Badano (LP)

Department of Cardiovascular, Neural and Metabolic Sciences, Istituto Auxologico Italiano IRCCS, Ospedale San Luca, Milano, Italy.
Department of Medicine and Surgery, University of Milano-Bicocca, Milano, Italy.

Gianfranco Parati (G)

Department of Cardiovascular, Neural and Metabolic Sciences, Istituto Auxologico Italiano IRCCS, Ospedale San Luca, Milano, Italy.
Department of Medicine and Surgery, University of Milano-Bicocca, Milano, Italy.

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