Mother brain is wired for social moments.
Oxytocin
attachment
human
mammalian sociality
maternal brain
neuroscience
social synchrony
Journal
eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614
Informations de publication
Date de publication:
25 03 2021
25 03 2021
Historique:
received:
28
05
2020
accepted:
22
03
2021
pubmed:
26
3
2021
medline:
4
9
2021
entrez:
25
3
2021
Statut:
epublish
Résumé
Reorganization of the maternal brain upon childbirth triggers the species-typical maternal social behavior. These brief social moments carry profound effects on the infant's brain and likely have a distinct signature in the maternal brain. Utilizing a double-blind, within-subject oxytocin/placebo administration crossover design, mothers' brain was imaged twice using fMRI while observing three naturalistic maternal-infant contexts in the home ecology; 'unavailable', 'unresponsive', and 'social', when mothers engaged in synchronous peek-a-boo play. The social condition elicited greater neural response across the human caregiving network, including amygdala, VTA, hippocampus, insula, ACC, and temporal cortex. Oxytocin impacted neural response primarily to the social condition and attenuated differences between social and non-social stimuli. Greater temporal consistency emerged in the 'social' condition across the two imaging sessions, particularly in insula, amygdala, and TP. Findings describe how mother's brain varies by caregiving experiences and gives salience to moments of social synchrony that support infant development and brain maturation.
Identifiants
pubmed: 33764299
doi: 10.7554/eLife.59436
pii: 59436
pmc: PMC8026217
doi:
pii:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2021, Shimon-Raz et al.
Déclaration de conflit d'intérêts
OS, RS, MB, GA, YY, AU, OZ, RF No competing interests declared
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