Patterns of multimorbidity and their association with hospitalisation: a population-based study of older adults in urban Tanzania.


Journal

Age and ageing
ISSN: 1468-2834
Titre abrégé: Age Ageing
Pays: England
ID NLM: 0375655

Informations de publication

Date de publication:
28 06 2021
Historique:
received: 01 09 2020
pubmed: 26 3 2021
medline: 7 8 2021
entrez: 25 3 2021
Statut: ppublish

Résumé

while the HIV epidemic remains a considerable challenge in sub-Saharan Africa, a dramatic reduction in the associated mortality has led to a fundamental shift in the public health priorities aimed at tackling multimorbidity. Against the unprecedented level of urbanisation taking place in Tanzania, the burden of multimorbidity and its consequences among ageing adults, in the form of costly inpatient hospitalisation, remain unquantified. we used data from one of Africa's largest urban population cohort, the Dar es Salaam Health and the Demographic Surveillance System, to quantity the extent of multimorbidity (occurrence of 2 ≥ health conditions) and discordant multimorbidity (occurrence of conditions in 2 ≥ domains in mental health, non-communicable and communicable health) among 2,299 adults aged ≥40 years in Dar es Salaam, Tanzania. We fitted logistic regression models to investigate the association between multimorbidity and inpatient hospitalisation. the prevalence of multimorbidity and discordant multimorbidity were 25.3 and 2.5%, respectively. Although the severe forms of multimorbidity (2.0% with ≥4 health conditions) and discordancy were low, hospitalisation was significantly higher based on the regression analyses. Household food insecurity was the only socio-economic variable that was significantly and consistently associated with a greater hospitalisation. we found an alarmingly high degree of multimorbidity among this ageing urban population where hospitalisation was driven by multimorbidity. As public health resources remain scarce, reducing costly inpatient hospitalisation requires multilevel interventions that address clinical- and structural-level challenges (e.g. food insecurity) to mitigate multimorbidity and promote long-term healthy independent living among older adults in Tanzania.

Sections du résumé

BACKGROUND
while the HIV epidemic remains a considerable challenge in sub-Saharan Africa, a dramatic reduction in the associated mortality has led to a fundamental shift in the public health priorities aimed at tackling multimorbidity. Against the unprecedented level of urbanisation taking place in Tanzania, the burden of multimorbidity and its consequences among ageing adults, in the form of costly inpatient hospitalisation, remain unquantified.
METHODS
we used data from one of Africa's largest urban population cohort, the Dar es Salaam Health and the Demographic Surveillance System, to quantity the extent of multimorbidity (occurrence of 2 ≥ health conditions) and discordant multimorbidity (occurrence of conditions in 2 ≥ domains in mental health, non-communicable and communicable health) among 2,299 adults aged ≥40 years in Dar es Salaam, Tanzania. We fitted logistic regression models to investigate the association between multimorbidity and inpatient hospitalisation.
RESULTS
the prevalence of multimorbidity and discordant multimorbidity were 25.3 and 2.5%, respectively. Although the severe forms of multimorbidity (2.0% with ≥4 health conditions) and discordancy were low, hospitalisation was significantly higher based on the regression analyses. Household food insecurity was the only socio-economic variable that was significantly and consistently associated with a greater hospitalisation.
CONCLUSION
we found an alarmingly high degree of multimorbidity among this ageing urban population where hospitalisation was driven by multimorbidity. As public health resources remain scarce, reducing costly inpatient hospitalisation requires multilevel interventions that address clinical- and structural-level challenges (e.g. food insecurity) to mitigate multimorbidity and promote long-term healthy independent living among older adults in Tanzania.

Identifiants

pubmed: 33765124
pii: 6188479
doi: 10.1093/ageing/afab046
pmc: PMC8522784
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

1349-1360

Subventions

Organisme : NIA NIH HHS
ID : P01 AG041710
Pays : United States

Informations de copyright

© The Author(s) 2021. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.

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Auteurs

Andrew Tomita (A)

Centre for Rural Health, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.
KwaZulu-Natal Research Innovation and Sequencing Platform, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.

Germana H Leyna (GH)

Department of Epidemiology & Biostatistics, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Center for Population and Development Studies, Harvard T. Chan School of Public Health, Boston, MA, USA.

Hae-Young Kim (HY)

KwaZulu-Natal Research Innovation and Sequencing Platform, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.
Department of Population Health, New York University Grossman School of Medicine, New York, NY, USA.
Africa Health Research Institute, KwaZulu-Natal, South Africa.

Yoshan Moodley (Y)

KwaZulu-Natal Research Innovation and Sequencing Platform, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.
Africa Health Research Institute, KwaZulu-Natal, South Africa.
School of Nursing and Public Health, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.

Emmanuel Mpolya (E)

Africa Health Research Institute, KwaZulu-Natal, South Africa.
Department of Global Health and Bio-Medical Sciences, School of Life Sciences and Bioengineering, Nelson Mandela African Institution of Science and Technology, Arusha, Tanzania.

Polycarp Mogeni (P)

KwaZulu-Natal Research Innovation and Sequencing Platform, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.
Africa Health Research Institute, KwaZulu-Natal, South Africa.
School of Nursing and Public Health, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.

Diego F Cuadros (DF)

Department of Geography and Geographic Information Science, University of Cincinnati, Cincinnati, USA.
Health Geography and Disease Modeling Laboratory, University of Cincinnati, Cincinnati, USA.

Armstrong Dzomba (A)

MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Alain Vandormael (A)

Heidelberg Institute of Global Health, University of Heidelberg, Heidelberg, Germany.

Till Bärnighausen (T)

Africa Health Research Institute, KwaZulu-Natal, South Africa.
Heidelberg Institute of Global Health, University of Heidelberg, Heidelberg, Germany.

Frank Tanser (F)

Africa Health Research Institute, KwaZulu-Natal, South Africa.
Lincoln International Institute for Rural Health, University of Lincoln, Lincoln, UK.
School of Nursing and Public Health, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.
Department of Population Health, London School of Hygiene and Tropical Medicine, London, UK.

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