Evaluation of cardiomyopathy diagnosis in heart transplant recipients: comparison of echocardiographic and pathologic classification.
Journal
The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology
ISSN: 2090-911X
Titre abrégé: Egypt Heart J
Pays: Germany
ID NLM: 9106952
Informations de publication
Date de publication:
25 Mar 2021
25 Mar 2021
Historique:
received:
14
11
2020
accepted:
16
03
2021
entrez:
25
3
2021
pubmed:
26
3
2021
medline:
26
3
2021
Statut:
epublish
Résumé
Definite diagnosis of cardiomyopathy types can be challenging in end-stage disease process. New growing data have suggested that there is inconsistency between echocardiography and pathology in defining type of cardiomyopathy before and after heart transplantation. The aim of the present study was to compare the pre-heart transplant echocardiographic diagnosis of cardiomyopathy with the results of post-transplant pathologic diagnosis. In this retrospective cross-sectional clinicopathological study, 100 consecutive patients have undergone heart transplantation in Masih-Daneshvari hospital, Tehran, Iran, between 2010 and 2019. The mean age of patients was 40 ± 13 years and 79% of patients were male. The frequency of different types of cardiomyopathy was significantly different between two diagnostic tools (echocardiography versus pathology, P < 0.001). On the other hand, in 24 patients, the results of echocardiography as regard to the type of cardiomyopathy were inconsistent with pathologic findings. Based on the findings of the present study, it could be concluded that there is a significant difference between echocardiographic and pathologic diagnosis of cardiomyopathy; therefore, it is necessary to use additional tools for definite diagnosis of cardiomyopathy like advanced cardiac imaging or even endomyocardial biopsy before heart transplantation to reach an appropriate treatment strategy.
Sections du résumé
BACKGROUND
BACKGROUND
Definite diagnosis of cardiomyopathy types can be challenging in end-stage disease process. New growing data have suggested that there is inconsistency between echocardiography and pathology in defining type of cardiomyopathy before and after heart transplantation. The aim of the present study was to compare the pre-heart transplant echocardiographic diagnosis of cardiomyopathy with the results of post-transplant pathologic diagnosis.
RESULTS
RESULTS
In this retrospective cross-sectional clinicopathological study, 100 consecutive patients have undergone heart transplantation in Masih-Daneshvari hospital, Tehran, Iran, between 2010 and 2019. The mean age of patients was 40 ± 13 years and 79% of patients were male. The frequency of different types of cardiomyopathy was significantly different between two diagnostic tools (echocardiography versus pathology, P < 0.001). On the other hand, in 24 patients, the results of echocardiography as regard to the type of cardiomyopathy were inconsistent with pathologic findings.
CONCLUSION
CONCLUSIONS
Based on the findings of the present study, it could be concluded that there is a significant difference between echocardiographic and pathologic diagnosis of cardiomyopathy; therefore, it is necessary to use additional tools for definite diagnosis of cardiomyopathy like advanced cardiac imaging or even endomyocardial biopsy before heart transplantation to reach an appropriate treatment strategy.
Identifiants
pubmed: 33765208
doi: 10.1186/s43044-021-00154-9
pii: 10.1186/s43044-021-00154-9
pmc: PMC7994484
doi:
Types de publication
Journal Article
Langues
eng
Pagination
29Références
Exp Clin Transplant. 2013 Aug;11(4):361-3
pubmed: 23113666
Rev Esp Cardiol (Engl Ed). 2016 Feb;69(2):178-87
pubmed: 26795929
Circulation. 2009 Oct 27;120(17):1725-41
pubmed: 19794121
Can J Cardiol. 2009 Feb;25(2):e48-54
pubmed: 19214301
Eur Heart J Cardiovasc Imaging. 2015 Mar;16(3):233-70
pubmed: 25712077
Eur J Heart Fail. 2016 Aug;18(8):891-975
pubmed: 27207191
Zhonghua Xin Xue Guan Bing Za Zhi. 2006 Nov;34(11):1005-8
pubmed: 17288765
Pediatr Cardiol. 2005 Jan-Feb;26(1):45-9
pubmed: 15793653
Circ J. 2017 Mar 24;81(4):417-426
pubmed: 28331134
Cardiovasc Pathol. 1999 Jan-Feb;8(1):17-23
pubmed: 10722244
Pathology. 2017 Dec;49(7):750-756
pubmed: 29021100
J Heart Lung Transplant. 2016 Jan;35(1):1-23
pubmed: 26776864
J Card Fail. 2007 Oct;13(8):643-8
pubmed: 17923356
Circ J. 2009 Jul;73(7):1235-9
pubmed: 19398842
Circulation. 2010 Aug 31;122(9):900-9
pubmed: 20713901
Curr Probl Cardiol. 2010 Apr;35(4):176-220
pubmed: 20197150
J Am Coll Cardiol. 2018 Mar 13;71(10):1149-1166
pubmed: 29519356
Acta Cardiol. 2006 Apr;61(2):169-74
pubmed: 16716018
N Engl J Med. 2000 Apr 13;342(15):1077-84
pubmed: 10760308
Postgrad Med. 2017 Jun;129(5):517-523
pubmed: 28440714