Hyaluronic acid/polyethyleneimine nanoparticles loaded with copper ion and disulfiram for esophageal cancer.
Animals
Antineoplastic Agents
/ administration & dosage
Apoptosis
/ drug effects
Carcinoma, Squamous Cell
/ drug therapy
Cells, Cultured
Copper
/ administration & dosage
Disulfiram
/ administration & dosage
Drug Carriers
/ chemical synthesis
Drug Delivery Systems
Drug Liberation
Esophageal Neoplasms
/ drug therapy
Heavy Ions
Humans
Hyaluronic Acid
/ chemical synthesis
Male
Mice
Mice, Inbred BALB C
Mice, Nude
Nanoparticles
/ chemistry
Polyethyleneimine
/ chemical synthesis
Xenograft Model Antitumor Assays
Disulfiram/Cu(2+)
Drug loaded nanoparticles
Effectiveness and targeting
Esophageal cancer
Hyaluronic acid
Journal
Carbohydrate polymers
ISSN: 1879-1344
Titre abrégé: Carbohydr Polym
Pays: England
ID NLM: 8307156
Informations de publication
Date de publication:
01 Jun 2021
01 Jun 2021
Historique:
received:
23
12
2020
revised:
04
02
2021
accepted:
18
02
2021
entrez:
26
3
2021
pubmed:
27
3
2021
medline:
4
5
2021
Statut:
ppublish
Résumé
In the clinical treatment of cancer, improving the effectiveness and targeting of drugs has always been a bottleneck problem that needs to be solved. In this contribution, inspired by the targeted inhibition on cancer from combination application of disulfiram and divalent copper ion (Cu
Identifiants
pubmed: 33766342
pii: S0144-8617(21)00233-2
doi: 10.1016/j.carbpol.2021.117846
pii:
doi:
Substances chimiques
Antineoplastic Agents
0
Drug Carriers
0
Copper
789U1901C5
Polyethyleneimine
9002-98-6
Hyaluronic Acid
9004-61-9
Disulfiram
TR3MLJ1UAI
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
117846Informations de copyright
Copyright © 2021 Elsevier Ltd. All rights reserved.