Platelets transfusion in Greece: Where, when, why? A national survey.
National
platelet
platelet products
platelets transfusion
survey
Journal
Asian journal of transfusion science
ISSN: 0973-6247
Titre abrégé: Asian J Transfus Sci
Pays: India
ID NLM: 101306858
Informations de publication
Date de publication:
Historique:
received:
14
06
2018
accepted:
02
06
2019
entrez:
26
3
2021
pubmed:
27
3
2021
medline:
27
3
2021
Statut:
ppublish
Résumé
Platelet transfusion is among the most useful therapeutic tools in modern clinical settings which mean that ensuring an adequate supply is of paramount importance. The aim of our study was to record the use and wastage of platelet concentrates (PCs) in Greece, so as to come up with evidence-based interventions. The study was conducted during May and June 2015. We evaluated the use of random-donor platelets (RDPs) and single-donor apheresis platelets (SDPs). We analyzed such parameters as hospital department and diagnosis, indication for transfusion, PCs' age at the time of transfusion, and wastage rate. We used data from 21 hospitals across the country. A total of 12,061 RDPs and 1189 SDPs were transfused, with an average of 4.84 (±2.72) and 1.12 (±2.73) units per episode, respectively. Most patients had been admitted to the internal medicine and hematology departments. The transfusions were mostly given prophylactically, usually in cases of acute leukemia, and mostly on the day before expiration. Wastage rate was 16.75% for RPDs and 2.70% for SDPs, primarily because of the expiration of the use-by date. This is the first national survey regarding platelet transfusion in Greece. Since most patients were admitted in internal medicine and hematology departments, we recommend that the staff of the abovementioned departments should undergo training on contemporary transfusion guidelines. Platelet discard rate could further be lowered through the centralization of inventory management along with the extension of the lifetime of PCs by means of emerging technologies.
Sections du résumé
BACKGROUND
BACKGROUND
Platelet transfusion is among the most useful therapeutic tools in modern clinical settings which mean that ensuring an adequate supply is of paramount importance.
AIM
OBJECTIVE
The aim of our study was to record the use and wastage of platelet concentrates (PCs) in Greece, so as to come up with evidence-based interventions.
METHODS
METHODS
The study was conducted during May and June 2015. We evaluated the use of random-donor platelets (RDPs) and single-donor apheresis platelets (SDPs). We analyzed such parameters as hospital department and diagnosis, indication for transfusion, PCs' age at the time of transfusion, and wastage rate.
RESULTS
RESULTS
We used data from 21 hospitals across the country. A total of 12,061 RDPs and 1189 SDPs were transfused, with an average of 4.84 (±2.72) and 1.12 (±2.73) units per episode, respectively. Most patients had been admitted to the internal medicine and hematology departments. The transfusions were mostly given prophylactically, usually in cases of acute leukemia, and mostly on the day before expiration. Wastage rate was 16.75% for RPDs and 2.70% for SDPs, primarily because of the expiration of the use-by date.
CONCLUSIONS
CONCLUSIONS
This is the first national survey regarding platelet transfusion in Greece. Since most patients were admitted in internal medicine and hematology departments, we recommend that the staff of the abovementioned departments should undergo training on contemporary transfusion guidelines. Platelet discard rate could further be lowered through the centralization of inventory management along with the extension of the lifetime of PCs by means of emerging technologies.
Identifiants
pubmed: 33767543
doi: 10.4103/ajts.AJTS_72_18
pii: AJTS-14-158
pmc: PMC7983137
doi:
Types de publication
Journal Article
Langues
eng
Pagination
158-166Informations de copyright
Copyright: © 2020 Asian Journal of Transfusion Science.
Déclaration de conflit d'intérêts
There are no conflicts of interest.
Références
Transfus Med Hemother. 2010 Jun;37(3):141-148
pubmed: 20737017
Transfusion. 2010 Dec;50(12):2565-70
pubmed: 20576016
Asian J Transfus Sci. 2012 Jan;6(1):19-23
pubmed: 22623837
Vox Sang. 2017 May;112(4):343-351
pubmed: 28261815
Health Syst Transit. 2017 Sep;19(5):1-166
pubmed: 29972131
Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):11368-11373
pubmed: 29073058
Transfusion. 2010 Aug;50(8):1743-8
pubmed: 20456712
Transfus Apher Sci. 2009 Oct;41(2):145-9
pubmed: 19716339
Vox Sang. 2014 Aug;107(2):103-13
pubmed: 24650183
Vox Sang. 2012 Aug;103(2):159-76
pubmed: 22519879
Transfusion. 2018 Mar;58(3):736-747
pubmed: 29266276
J Clin Oncol. 2018 Jan 20;36(3):283-299
pubmed: 29182495
Turk J Haematol. 2017 Mar 1;34(1):52-58
pubmed: 27873739
Thromb Res. 2009 Nov;124(5):e13-8
pubmed: 19631969
Transfus Med. 2019 Feb;29(1):28-32
pubmed: 29230899
Transfus Med. 2014 Aug;24(4):213-8
pubmed: 24957661
Transfusion. 2018 Jan;58(1):16-24
pubmed: 29168187
Hematology Am Soc Hematol Educ Program. 2015;2015:462-70
pubmed: 26637759
Vox Sang. 2016 May;110(4):369-75
pubmed: 26830874
Transfus Med. 2017 Oct;27 Suppl 5:348-353
pubmed: 28661077
Br J Haematol. 2017 Feb;176(3):365-394
pubmed: 28009056
Ann Intern Med. 2015 Feb 03;162(3):205-13
pubmed: 25383671
Vox Sang. 2012 Nov;103(4):284-93
pubmed: 22775395
Vox Sang. 2018 May;113(4):317-328
pubmed: 29441601
Transfus Apher Sci. 2014 Dec;51(3):44-52
pubmed: 25457007