Clinical and demographic differences between idiopathic intracranial hypertension patients with mild and severe papilledema.
Demographics
idiopathic intracranial hypertension
papilledema
visual outcome
Journal
Taiwan journal of ophthalmology
ISSN: 2211-5072
Titre abrégé: Taiwan J Ophthalmol
Pays: India
ID NLM: 101582127
Informations de publication
Date de publication:
Historique:
received:
11
06
2020
accepted:
13
07
2020
entrez:
26
3
2021
pubmed:
27
3
2021
medline:
27
3
2021
Statut:
epublish
Résumé
The purpose of this study was to evaluate whether papilledema severity is associated with specific demographic or clinical factors in patients with idiopathic intracranial hypertension (IIH). A retrospective cohort study of consecutive IIH patients seen at one tertiary care institution between 1989 and March 31, 2017 was performed. IIH patients were classified as mild (Frisén Grade 1 or 2) or severe (Frisén Grade 4 or 5) based on grading of fundus photographs obtained at first presentation. Demographic and clinical variables including age, body mass index (BMI), gender, visual acuity, Humphrey visual field mean deviation, and cerebrospinal fluid (CSF) opening pressure were extracted from patient medical records for statistical analyses. A total of 239 patients were included in the study: 152 with mild papilledema and 87 with severe papilledema. There was no difference in age, race, BMI, or male gender between the mild and severe papilledema groups. CSF opening pressure was significantly higher in the severe papilledema group (41.89 cm of water vs. 33.69, 95% confidence interval [CI]: -10.79--5.62, Age, race, sex, and BMI were similar in IIH patients with mild versus severe papilledema, emphasizing the importance of a dilated fundus examination to reliably stratify patients. Patients with severe papilledema are at higher risk of visual acuity and visual field loss at final follow-up.
Identifiants
pubmed: 33767955
doi: 10.4103/tjo.tjo_44_20
pii: TJO-11-53
pmc: PMC7971438
doi:
Types de publication
Journal Article
Langues
eng
Pagination
53-56Informations de copyright
Copyright: © 2020 Taiwan J Ophthalmol.
Déclaration de conflit d'intérêts
The authors declare that there are no conflicts of interests of this paper.
Références
Neurology. 2009 Jan 27;72(4):304-9
pubmed: 18923135
N Engl J Med. 2020 Apr 30;382(18):1687-1695
pubmed: 32286748
Continuum (Minneap Minn). 2019 Oct;25(5):1289-1309
pubmed: 31584538
Can J Neurol Sci. 2020 Sep;47(5):661-665
pubmed: 32362301
Br J Ophthalmol. 2016 Apr;100(4):505-9
pubmed: 26269534
J Neuroophthalmol. 2011 Jun;31(2):175-86
pubmed: 21593630
Neurology. 2015 Sep 1;85(9):799-805
pubmed: 26245929
Invest Ophthalmol Vis Sci. 1998 Jan;39(1):134-42
pubmed: 9430554
Invest Ophthalmol Vis Sci. 2015 May;56(5):3292-303
pubmed: 26024112
Am J Ophthalmol. 2003 Apr;135(4):437-46
pubmed: 12654358
Arch Neurol. 1982 Aug;39(8):461-74
pubmed: 7103794
Neurology. 2008 Mar 11;70(11):861-7
pubmed: 18332344
J Neurol. 2012 Jul;259(7):1406-12
pubmed: 22237821
Clin Neurol Neurosurg. 2015 Sep;136:95-9
pubmed: 26093225
Br J Ophthalmol. 2019 Oct;103(10):1429-1435
pubmed: 30530819
Brain. 1991 Feb;114 ( Pt 1A):155-80
pubmed: 1998880
Am J Ophthalmol. 2018 Nov;195:101-109
pubmed: 30081012
Ophthalmology. 1984 Nov;91(11):1303-12
pubmed: 6514295
J Neuroophthalmol. 2013 Mar;33(1):4-8
pubmed: 22217456
Neurology. 2018 Jan 23;90(4):167-175
pubmed: 29273687
Ophthalmology. 2015 Sep;122(9):1939-45.e2
pubmed: 26198807
Arch Ophthalmol. 2010 Jun;128(6):705-11
pubmed: 20547947