Evaluation of Ac-Lys

800CW-TATE Intra-operative guidance Meningioma Molecular fluorescence guided surgery Somatostatin receptor subtype 2

Journal

Journal of neuro-oncology
ISSN: 1573-7373
Titre abrégé: J Neurooncol
Pays: United States
ID NLM: 8309335

Informations de publication

Date de publication:
Jun 2021
Historique:
received: 26 01 2021
accepted: 12 03 2021
pubmed: 27 3 2021
medline: 15 12 2021
entrez: 26 3 2021
Statut: ppublish

Résumé

Meningioma recurrence rates can be reduced by optimizing surgical resection with the use of intraoperative molecular fluorescence guided surgery (MFGS). We evaluated the potential of the fluorescent tracer 800CW-TATE for MFGS using in vitro and in vivo models. It targets somatostatin receptor subtype 2 (SSTR Binding affinity of 800CW-TATE was evaluated using [ 800CW-TATE binding affinity assays showed an IC 800CW-TATE demonstrated sufficient binding affinity, specific SSTR

Identifiants

pubmed: 33768405
doi: 10.1007/s11060-021-03739-1
pii: 10.1007/s11060-021-03739-1
pmc: PMC8211583
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

211-222

Commentaires et corrections

Type : ErratumIn

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Auteurs

Bianca M Dijkstra (BM)

Department of Neurosurgery, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30.001, 9700 VB, Groningen, The Netherlands.

Marion de Jong (M)

Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands.

Marcus C M Stroet (MCM)

Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands.
Department of Molecular Genetics, Oncode Institute, Erasmus MC, Rotterdam, The Netherlands.

Fritz Andreae (F)

piCHEM Forschungs und EntwicklungsGmbH, Raaba-Grambach, Graz, Austria.

Sebastiaan E Dulfer (SE)

Department of Neurosurgery, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30.001, 9700 VB, Groningen, The Netherlands.

Marieke Everts (M)

Department of Medical Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Schelto Kruijff (S)

Department of Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Julie Nonnekens (J)

Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands.
Department of Molecular Genetics, Oncode Institute, Erasmus MC, Rotterdam, The Netherlands.

Wilfred F A den Dunnen (WFA)

Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Frank A E Kruyt (FAE)

Department of Medical Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Rob J M Groen (RJM)

Department of Neurosurgery, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30.001, 9700 VB, Groningen, The Netherlands. r.j.m.groen@umcg.nl.

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