Exploring Sustainability in the Era of Differentiated HIV Service Delivery in Sub-Saharan Africa: A Systematic Review.


Journal

Journal of acquired immune deficiency syndromes (1999)
ISSN: 1944-7884
Titre abrégé: J Acquir Immune Defic Syndr
Pays: United States
ID NLM: 100892005

Informations de publication

Date de publication:
01 08 2021
Historique:
received: 12 06 2020
accepted: 01 03 2021
pubmed: 27 3 2021
medline: 25 2 2023
entrez: 26 3 2021
Statut: ppublish

Résumé

The World Health Organization recommends differentiated service delivery (DSD) to support resource-limited health systems in providing patient-centered HIV care. DSD offers alternative care models to clinic-based care for people living with HIV who are stable on antiretroviral therapy (ART). Despite good patient-related outcomes, there is limited evidence of their sustainability. Our review evaluated the reporting of sustainability indicators of DSD interventions conducted in sub-Saharan Africa (SSA). We searched PubMed and EMBASE for studies conducted between 2000 and 2019 assessing DSD interventions targeting HIV-positive individuals who are established in ART in sub-Saharan Africa. We evaluated them through a comprehensive sustainability framework of constructs categorized into 6 domains (intervention design, process, external environment, resources, organizational setting, and people involvement). We scored each construct 1, 2, or 3 for no, partial, or sufficient level of evidence, respectively. Interventions with a calculated sustainability score (overall and domain-specific) of >90% or domain-specific median score >2.7 were considered likely to be sustainable. Overall scores ranged from 69% to 98%. Top scoring intervention types included adherence clubs (98%) and community ART groups (95%) which comprised more than half of interventions. The highest scoring domains were design (2.9) and organizational setting (2.8). The domains of resources (2.4) and people involvement (2.3) scored lowest revealing potential areas for improvement to support DSD sustainability. With the right investment in stakeholder involvement and domestic funding, DSD models generally show potential for sustainability. Our results could guide informed decisions on which DSD intervention is likely to be sustainable per setting and highlight areas that could motivate further research.

Identifiants

pubmed: 33770063
doi: 10.1097/QAI.0000000000002688
pii: 00126334-202108010-00007
pmc: PMC8219088
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1055-1071

Subventions

Organisme : World Health Organization
ID : 001
Pays : International
Organisme : Department of Health
Pays : United Kingdom

Informations de copyright

Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc.

Déclaration de conflit d'intérêts

The authors have no funding or conflicts of interest to disclose.

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Auteurs

Nwanneka E Okere (NE)

Department of Global Health, Amsterdam Institute for Global Health and Development, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.

Laura Lennox (L)

Department of Primary Care and Public health, Imperial College, National Institute for Health Research, Applied Research Collaboration, North West London, London, United Kingdom.

Lisa Urlings (L)

Department of Medicine, Amsterdam UMC University of Amsterdam, Amsterdam, Netherlands.

Nathan Ford (N)

Department HIV, World Health Organization, Geneva, Switzerland.
Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa.

Denise Naniche (D)

ISGlobal, Barcelona Institute for Global Health, Hospital Clinic-University of Barcelona, Barcelona, Spain.

Tobias F Rinke de Wit (TF)

Department of Global Health, Amsterdam Institute for Global Health and Development, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.

Sabine Hermans (S)

Department of Global Health, Amsterdam Institute for Global Health and Development, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.

Gabriela B Gomez (GB)

Department of Global Health and Development, London School of Health and Tropical Medicine, London, United Kingdom ; and.
Department of Modelling, Epidemiology and Data Science, Currently, Sanofi Pasteur, Lyon, France .

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