Incidence and pathophysiology of diabetes in South Asian adults living in India and Pakistan compared with US blacks and whites.
India
diabetes mellitus
epidemiology
ethnic groups
type 2
Journal
BMJ open diabetes research & care
ISSN: 2052-4897
Titre abrégé: BMJ Open Diabetes Res Care
Pays: England
ID NLM: 101641391
Informations de publication
Date de publication:
03 2021
03 2021
Historique:
received:
28
09
2020
revised:
11
02
2021
accepted:
16
02
2021
entrez:
27
3
2021
pubmed:
28
3
2021
medline:
22
6
2021
Statut:
ppublish
Résumé
We compared diabetes incidence in South Asians aged ≥45 years in urban India (Chennai and Delhi) and Pakistan (Karachi), two low-income and middle-income countries undergoing rapid transition, with blacks and whites in the US, a high-income country. We computed age-specific, sex-specific and body mass index (BMI)-specific diabetes incidence from the prospective Center for Cardiometabolic Risk Reduction in South Asia Study (n=3136) and the Atherosclerosis Risk in Communities Study (blacks, n=3059; whites, n=9924). We assessed factors associated with incident diabetes using Cox proportional hazards regression. South Asians have lower BMI and waist circumference than blacks and whites (median BMI, kg/m South Asian adults have lower BMI and are less insulin resistant than US blacks and whites, but have higher diabetes incidence than US whites, especially in subgroups without obesity. Factors other than insulin resistance (ie, insulin secretion) may play an important role in the natural history of diabetes in South Asians.
Identifiants
pubmed: 33771764
pii: 9/1/e001927
doi: 10.1136/bmjdrc-2020-001927
pmc: PMC8006839
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NIDDK NIH HHS
ID : P30 DK111024
Pays : United States
Organisme : NCATS NIH HHS
ID : KL2 TR002381
Pays : United States
Organisme : NHLBI NIH HHS
ID : HHSN268201700004I
Pays : United States
Organisme : NHLBI NIH HHS
ID : HHSN268201700002I
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL125442
Pays : United States
Organisme : NHLBI NIH HHS
ID : HHSN268201700005I
Pays : United States
Organisme : NHLBI NIH HHS
ID : HHSN268200900026C
Pays : United States
Organisme : NHLBI NIH HHS
ID : HHSN268201700003I
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR002378
Pays : United States
Organisme : FIC NIH HHS
ID : D43 TW009135
Pays : United States
Organisme : NHLBI NIH HHS
ID : K24 HL152440
Pays : United States
Organisme : Wellcome Trust
ID : WT084754/Z/08/A
Pays : United Kingdom
Organisme : NHLBI NIH HHS
ID : HHSN268201700001I
Pays : United States
Commentaires et corrections
Type : CommentIn
Informations de copyright
© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
Références
Diabetologia. 2020 Jun;63(6):1103-1109
pubmed: 32236731
Nutr Rev. 2001 Jan;59(1 Pt 1):1-9
pubmed: 11281246
Int J Obes (Lond). 2008 Aug;32 Suppl 3:S56-9
pubmed: 18695655
Diabetes Care. 2015 Aug;38(8):1441-8
pubmed: 25906786
Br Med J (Clin Res Ed). 1985 Oct 19;291(6502):1081-4
pubmed: 3931804
Diabetes Care. 2009 Sep;32(9):1644-6
pubmed: 19509010
Br Heart J. 1994 Nov;72(5):413-21
pubmed: 7818957
Diabetes Metab Res Rev. 2019 Nov;35(8):e3192
pubmed: 31145829
Diabetologia. 1985 Jul;28(7):412-9
pubmed: 3899825
Diabetologia. 2013 Jun;56(6):1272-81
pubmed: 23494447
Diabetes Care. 2020 Aug;43(8):1948-1957
pubmed: 33534728
Am J Public Health. 2010 Apr;100(4):661-8
pubmed: 19608956
Diabetes Care. 2011 Aug;34(8):1741-8
pubmed: 21680722
Diabetologia. 2006 Jun;49(6):1175-8
pubmed: 16570158
CMAJ. 2010 May 18;182(8):781-9
pubmed: 20403889
Diabetes Care. 2011 Jan;34(1):96-101
pubmed: 20978094
Diabetes Care. 2011 Aug;34(8):1791-3
pubmed: 21715521
J Diabetes Complications. 2014 Jan-Feb;28(1):45-50
pubmed: 24211090
BMC Public Health. 2012 May 25;12:380
pubmed: 22630043
Diabetes Technol Ther. 2013 Apr;15(4):315-22
pubmed: 23484483
Lancet. 1991 Feb 16;337(8738):382-6
pubmed: 1671422
J Assoc Physicians India. 2008 Mar;56:152-7
pubmed: 18697630
Nutrition. 2001 Jan;17(1):26-30
pubmed: 11165884
J Clin Endocrinol Metab. 2001 Nov;86(11):5366-71
pubmed: 11701707
Lancet Diabetes Endocrinol. 2017 Aug;5(8):585-596
pubmed: 28601585
J Clin Epidemiol. 1996 Feb;49(2):223-33
pubmed: 8606324
BMC Public Health. 2012 Aug 28;12:701
pubmed: 22928740
J Diabetes. 2010 Jun;2(2):118-24
pubmed: 20923494
Diabetes Care. 2004 Jun;27(6):1487-95
pubmed: 15161807
Diabetes Res Clin Pract. 2018 Dec;146:34-40
pubmed: 30244052
Br J Nutr. 2009 Aug;102(4):632-41
pubmed: 19203416
Diabetes Care. 2015 Jul;38(7):1312-8
pubmed: 25877810
Diabetes Care. 2013 Sep;36(9):2772-8
pubmed: 23596180
Diabetes Care. 2003 Jun;26(6):1770-80
pubmed: 12766108
Diabetes Res Clin Pract. 2015 Nov;110(2):172-82
pubmed: 26432412
Diabetes Care. 2013 Mar;36(3):574-9
pubmed: 23069837
Metab Syndr Relat Disord. 2003 Dec;1(4):277-83
pubmed: 18370652
Diabet Med. 2002 Jul;19(7):527-34
pubmed: 12099954
Metab Syndr Relat Disord. 2010 Apr;8(2):157-64
pubmed: 19943798