Histopathological comparison of pleomorphic adenomas of the parotid and submandibular gland.
capsule
parotid gland
pleomorphic adenoma
satellite nodules
submandibular gland
Journal
Oral diseases
ISSN: 1601-0825
Titre abrégé: Oral Dis
Pays: Denmark
ID NLM: 9508565
Informations de publication
Date de publication:
May 2022
May 2022
Historique:
revised:
10
03
2021
received:
17
02
2021
accepted:
19
03
2021
pubmed:
28
3
2021
medline:
29
4
2022
entrez:
27
3
2021
Statut:
ppublish
Résumé
The aim of this study was to investigate and compare the histopathological findings in pleomorphic adenomas (PA) of the parotid and submandibular gland with emphasis on the histological subtype and capsular characteristics. The histopathological specimens of all patients with PAs of the parotid and submandibular gland between 2000 and 2020 were re-examined by an experienced head and neck pathologist. Patients without representative slides allowing evaluation of the whole periphery of the PA were excluded from our study sample. Nine hundred and thirty-four patients formed our study sample (327 men, 607 women, male-to-female ratio: 0.53:1). Eight hundred and forty-four cases had a PA in the parotid gland and the remaining 90 in the submandibular gland. Our comparative analysis showed that submandibular PAs are characterized by the consistent presence of an intact anatomical capsule, infrequent occurrence of pseudopodia and satellite nodules, and a low proportion of the high-risk myxoid subtype. Our study highlights significant differences between PAs of the parotid and submandibular glands in their histopathological characteristics. Their differences likely underlie the favorable surgical outcome observed in PAs of the submandibular glands and may explain the propensity of PAs of the parotid glands for local recurrences.
Types de publication
Journal Article
Langues
eng
Pagination
1131-1136Informations de copyright
© 2021 The Authors. Oral Diseases published by Wiley Periodicals LLC.
Références
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