An Insight into Non-Covalent Interactions on the Bicyclo[1.1.1]pentane Scaffold.

Bicyclo[1.1.1]pentane Bioisosteres Halogen bonding Hydrogen bonding Noncovalent interactions

Journal

European journal of organic chemistry
ISSN: 1434-193X
Titre abrégé: European J Org Chem
Pays: Germany
ID NLM: 9805750

Informations de publication

Date de publication:
19 Feb 2021
Historique:
received: 30 11 2020
revised: 03 12 2020
entrez: 29 3 2021
pubmed: 30 3 2021
medline: 30 3 2021
Statut: ppublish

Résumé

Bicyclo[1.1.1]pentane (BCP) is studied extensively as a bioisosteric component of drugs. Not found in nature, this molecular unit approximates the distance of a

Identifiants

pubmed: 33776556
doi: 10.1002/ejoc.202001564
pii: EJOC202001564
pmc: PMC7986844
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1113-1122

Informations de copyright

© 2020 The Authors. European Journal of Organic Chemistry published by Wiley-VCH GmbH.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

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Auteurs

Nitika Grover (N)

School of Chemistry Trinity Biomedical Sciences Institute Trinity College Dublin The University of Dublin 152-160 Pearse Street Dublin 2 Ireland.

Keith J Flanagan (KJ)

School of Chemistry Trinity Biomedical Sciences Institute Trinity College Dublin The University of Dublin 152-160 Pearse Street Dublin 2 Ireland.

Cristina Trujillo (C)

School of Chemistry Trinity Biomedical Sciences Institute Trinity College Dublin The University of Dublin 152-160 Pearse Street Dublin 2 Ireland.

Christopher J Kingsbury (CJ)

School of Chemistry Trinity Biomedical Sciences Institute Trinity College Dublin The University of Dublin 152-160 Pearse Street Dublin 2 Ireland.

Mathias O Senge (MO)

Institute for Advanced Study (TUM-IAS) Technical University of Munich, Focus Group - Molecular and Interfacial Engineering of Organic Nanosystems Lichtenberg-Str. 2a 85748 Garching Germany.

Classifications MeSH