Expanding the Phenotype of

Autism Expanding phenotype Hypoplastic right caudate nucleus body Neuroimaging Novel pathogenic variant TUBB2A Tubulinopathy Whole-exome sequencing Whole-genome sequencing

Journal

Molecular syndromology
ISSN: 1661-8769
Titre abrégé: Mol Syndromol
Pays: Switzerland
ID NLM: 101525192

Informations de publication

Date de publication:
Mar 2021
Historique:
received: 02 05 2020
accepted: 08 10 2020
entrez: 29 3 2021
pubmed: 30 3 2021
medline: 30 3 2021
Statut: ppublish

Résumé

Tubulinopathies are a group of conditions caused by variants in 6 tubulin genes that present with a spectrum of brain malformations. One of these conditions is

Identifiants

pubmed: 33776625
doi: 10.1159/000512160
pii: msy-0012-0033
pmc: PMC7983673
doi:

Types de publication

Case Reports

Langues

eng

Pagination

33-40

Informations de copyright

Copyright © 2020 by S. Karger AG, Basel.

Déclaration de conflit d'intérêts

I.W.M. and M.J.G.S. are employees of GeneDx, Inc. A.M., D.P., and A.C. are employees of Illumina, Inc. Other authors have no conflicts of interest to declare.

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Auteurs

Lindsey Schmidt (L)

Sanford Health, Augustana-Sanford Genetic Counseling Program, Sioux Falls, South Dakota, USA.

Karen E Wain (KE)

Geisinger Autism & Developmental Medicine Institute, Lewisburg, Pennsylvania, USA.

Catherine Hajek (C)

Sanford Health, Sioux Falls, South Dakota, USA.

Juvianee I Estrada-Veras (JI)

Henry M Jackson Foundation for the Advancement of Military Medicine and Walter Reed National Military Medical Center, Bethesda, Maryland, USA.

Maria J Guillen Sacoto (MJ)

GeneDx, Gaithersburg, Maryland, USA.

Ingrid M Wentzensen (IM)

GeneDx, Gaithersburg, Maryland, USA.

Alka Malhotra (A)

Illumina Clinical Services Laboratory, San Diego, California, USA.

Amanda Clause (A)

Illumina Clinical Services Laboratory, San Diego, California, USA.

Denise Perry (D)

Illumina Clinical Services Laboratory, San Diego, California, USA.

Andres Moreno-De-Luca (A)

Department of Radiology, Geisinger Autism & Developmental Medicine Institute, Genomic Medicine Institute, Lewisburg, Pennsylvania, USA.

Megan Bell (M)

Sanford Health, Sioux Falls, South Dakota, USA.

Classifications MeSH