Myocardial Late Iodine Enhancement and Extracellular Volume Quantification with Dual-Layer Spectral Detector Dual-Energy Cardiac CT.

Journal

Radiology. Cardiothoracic imaging
ISSN: 2638-6135
Titre abrégé: Radiol Cardiothorac Imaging
Pays: United States
ID NLM: 101748663

Informations de publication

Date de publication:
Apr 2019
Historique:
received: 29 07 2018
revised: 01 02 2019
accepted: 06 02 2019
entrez: 29 3 2021
pubmed: 25 4 2019
medline: 25 4 2019
Statut: epublish

Résumé

To explore the usefulness of myocardial late iodine enhancement (LIE) and extracellular volume (ECV) quantification by using dual-energy cardiac CT. In this single-center retrospective study, a total of 40 patients were evaluated with LIE CT by using a dual-layer spectral detector CT system. Among these, 21 also underwent cardiac MRI. Paired image sets were created by using standard imaging at 120 kVp, virtual monochromatic imaging (VMI) at 50 keV, and iodine density imaging. The contrast-to-noise ratio and image quality were then compared. Two observers assessed the presence of LIE and calculated the interobserver agreements. Agreement between CT and cardiac MRI when detecting late-enhancing lesions and calculating the ECV was also assessed. The contrast-to-noise ratio was significantly higher by using VMI than by using standard 120-kVp imaging, and the mean visual image quality score was significantly higher by using VMI than by using either standard or iodine density imaging. For interobserver agreement of visual detection of LIE, the agreement for VMI was excellent and the κ value (κ, 0.87) was higher than that for the standard 120-kVp (κ, 0.70) and iodine density (κ, 0.83) imaging. For detecting late-enhancing lesions, agreement with cardiac MRI was excellent by using VMI (κ, 0.90) and iodine density imaging (κ, 0.87) but was only good by using standard 120-kVp imaging (κ, 0.66). Quantitative comparisons of the ECV calculations by using CT and cardiac MRI showed excellent correlation ( Dual-energy cardiac CT can assess myocardial LIE and quantify ECV, with results comparable to those obtained by using cardiac MRI.© RSNA, 2019See also the commentary by Litt in this issue.

Identifiants

DOI: 10.1148/ryct.2019180003 PMID: 33778497 PMC: PMC7977749
pubmed: 33778497
doi: 10.1148/ryct.2019180003
pmc: PMC7977749
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e180003

Commentaires et corrections

Type : CommentIn

Informations de copyright

2019 by the Radiological Society of North America, Inc.

Déclaration de conflit d'intérêts

Disclosures of Conflicts of Interest: S.O. disclosed no relevant relationships. T.E. disclosed no relevant relationships. T.N. disclosed no relevant relationships. M.K. disclosed no relevant relationships. D.U. disclosed no relevant relationships. Y.F. disclosed no relevant relationships. Y.N. disclosed no relevant relationships. S.T. disclosed no relevant relationships. M.U. disclosed no relevant relationships. T.Y. disclosed no relevant relationships. K.T. disclosed no relevant relationships. Y.A. disclosed no relevant relationships. Y.Y. disclosed no relevant relationships.

Références

J Comput Assist Tomogr. 2017 Sep/Oct;41(5):750-756
pubmed: 28240638
Eur J Radiol. 2018 Jan;98:118-125
pubmed: 29279149
Radiology. 2015 Feb;274(2):370-8
pubmed: 25247406
Eur Radiol. 2012 Oct;22(10):2117-24
pubmed: 22618521
IEEE Trans Med Imaging. 1988;7(3):218-24
pubmed: 18230472
J Cardiovasc Comput Tomogr. 2015 Nov-Dec;9(6):585-92
pubmed: 26209459
Radiology. 2012 Sep;264(3):876-83
pubmed: 22771879
Radiographics. 2006 May-Jun;26(3):795-810
pubmed: 16702455
Eur Radiol. 2018 Jul;28(7):2745-2755
pubmed: 29404773
Eur Radiol. 2019 Jun;29(6):2837-2847
pubmed: 30377793
Cardiovasc Diagn Ther. 2017 Apr;7(2):159-170
pubmed: 28540211
Circulation. 2010 Jul 13;122(2):138-44
pubmed: 20585010
JACC Cardiovasc Imaging. 2013 Oct;6(10):1062-1071
pubmed: 24011773
Eur Radiol. 2017 Oct;27(10):4351-4359
pubmed: 28374079
J Cardiovasc Magn Reson. 2017 Oct 9;19(1):75
pubmed: 28992817
Eur J Radiol. 2017 Aug;93:52-58
pubmed: 28668431
AJR Am J Roentgenol. 2010 Sep;195(3):639-46
pubmed: 20729440
Radiology. 2018 Sep;288(3):682-691
pubmed: 29989514
AJR Am J Roentgenol. 2016 Jun;206(6):1222-32
pubmed: 27058192
Clin Imaging. 2018 Nov - Dec;52:292-301
pubmed: 30212800
Radiology. 2018 May;287(2):442-451
pubmed: 29272215
J Cardiovasc Comput Tomogr. 2010 Nov-Dec;4(6):407.e1-33
pubmed: 21232696
Radiology. 2011 Apr;259(1):257-62
pubmed: 21330561
Radiology. 2016 Jul;280(1):49-57
pubmed: 27322972
J Cardiovasc Magn Reson. 2016 Jan 22;18:6
pubmed: 26800662
Invest Radiol. 2013 Aug;48(8):598-606
pubmed: 23511193
Eur Radiol. 2018 Apr;28(4):1719-1730
pubmed: 29063254
Eur Radiol. 2015 Aug;25(8):2493-501
pubmed: 25680727
Phys Med. 2018 May;49:5-10
pubmed: 29866343
Eur Radiol. 2018 Aug;28(8):3393-3404
pubmed: 29460075
Radiology. 2013 Nov;269(2):396-403
pubmed: 23878282
Invest Radiol. 2012 May;47(5):292-8
pubmed: 22472797
J Am Coll Cardiol. 2011 Feb 22;57(8):891-903
pubmed: 21329834
Nat Rev Cardiol. 2009 Nov;6(11):699-710
pubmed: 19851349
JACC Cardiovasc Imaging. 2012 Aug;5(8):829-36
pubmed: 22897997
Eur Radiol. 2016 Jun;26(6):1863-70
pubmed: 26334508
Invest Radiol. 2013 Dec;48(12):851-6
pubmed: 23907104
J Cardiovasc Comput Tomogr. 2017 Jan - Feb;11(1):33-39
pubmed: 28096049
Br J Radiol. 2017 Oct;90(1078):20170290
pubmed: 28749176

Auteurs

Seitaro Oda (S)

Departments of Diagnostic Radiology (S.O., T.N., M.K., D.U., Y.N., Y.Y.), Medical Physics (Y.F.), Cardiology (S.T., K.T.), and Neurology (M.U., T.Y., Y.A.), Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuo-ku, Kumamoto 860-8556, Japan; and Department of Central Radiology, Kumamoto University Hospital, Kumamoto, Japan (T.E.).
ORCID: 0000-0003-4101-5113

Takafumi Emoto (T)

Departments of Diagnostic Radiology (S.O., T.N., M.K., D.U., Y.N., Y.Y.), Medical Physics (Y.F.), Cardiology (S.T., K.T.), and Neurology (M.U., T.Y., Y.A.), Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuo-ku, Kumamoto 860-8556, Japan; and Department of Central Radiology, Kumamoto University Hospital, Kumamoto, Japan (T.E.).
ORCID: 0000-0002-3258-4085

Takeshi Nakaura (T)

Departments of Diagnostic Radiology (S.O., T.N., M.K., D.U., Y.N., Y.Y.), Medical Physics (Y.F.), Cardiology (S.T., K.T.), and Neurology (M.U., T.Y., Y.A.), Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuo-ku, Kumamoto 860-8556, Japan; and Department of Central Radiology, Kumamoto University Hospital, Kumamoto, Japan (T.E.).
ORCID: 0000-0002-9010-0341

Masafumi Kidoh (M)

Departments of Diagnostic Radiology (S.O., T.N., M.K., D.U., Y.N., Y.Y.), Medical Physics (Y.F.), Cardiology (S.T., K.T.), and Neurology (M.U., T.Y., Y.A.), Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuo-ku, Kumamoto 860-8556, Japan; and Department of Central Radiology, Kumamoto University Hospital, Kumamoto, Japan (T.E.).
ORCID: 0000-0002-9589-7054

Daisuke Utsunomiya (D)

Departments of Diagnostic Radiology (S.O., T.N., M.K., D.U., Y.N., Y.Y.), Medical Physics (Y.F.), Cardiology (S.T., K.T.), and Neurology (M.U., T.Y., Y.A.), Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuo-ku, Kumamoto 860-8556, Japan; and Department of Central Radiology, Kumamoto University Hospital, Kumamoto, Japan (T.E.).
ORCID: 0000-0002-1723-1724

Yoshinori Funama (Y)

Departments of Diagnostic Radiology (S.O., T.N., M.K., D.U., Y.N., Y.Y.), Medical Physics (Y.F.), Cardiology (S.T., K.T.), and Neurology (M.U., T.Y., Y.A.), Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuo-ku, Kumamoto 860-8556, Japan; and Department of Central Radiology, Kumamoto University Hospital, Kumamoto, Japan (T.E.).
ORCID: 0000-0003-1797-9625

Yasunori Nagayama (Y)

Departments of Diagnostic Radiology (S.O., T.N., M.K., D.U., Y.N., Y.Y.), Medical Physics (Y.F.), Cardiology (S.T., K.T.), and Neurology (M.U., T.Y., Y.A.), Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuo-ku, Kumamoto 860-8556, Japan; and Department of Central Radiology, Kumamoto University Hospital, Kumamoto, Japan (T.E.).
ORCID: 0000-0003-3280-7346

Seiji Takashio (S)

Departments of Diagnostic Radiology (S.O., T.N., M.K., D.U., Y.N., Y.Y.), Medical Physics (Y.F.), Cardiology (S.T., K.T.), and Neurology (M.U., T.Y., Y.A.), Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuo-ku, Kumamoto 860-8556, Japan; and Department of Central Radiology, Kumamoto University Hospital, Kumamoto, Japan (T.E.).
ORCID: 0000-0002-6201-0701

Mitsuharu Ueda (M)

Departments of Diagnostic Radiology (S.O., T.N., M.K., D.U., Y.N., Y.Y.), Medical Physics (Y.F.), Cardiology (S.T., K.T.), and Neurology (M.U., T.Y., Y.A.), Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuo-ku, Kumamoto 860-8556, Japan; and Department of Central Radiology, Kumamoto University Hospital, Kumamoto, Japan (T.E.).
ORCID: 0000-0002-6814-0582

Taro Yamashita (T)

Departments of Diagnostic Radiology (S.O., T.N., M.K., D.U., Y.N., Y.Y.), Medical Physics (Y.F.), Cardiology (S.T., K.T.), and Neurology (M.U., T.Y., Y.A.), Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuo-ku, Kumamoto 860-8556, Japan; and Department of Central Radiology, Kumamoto University Hospital, Kumamoto, Japan (T.E.).

Kenichi Tsujita (K)

Departments of Diagnostic Radiology (S.O., T.N., M.K., D.U., Y.N., Y.Y.), Medical Physics (Y.F.), Cardiology (S.T., K.T.), and Neurology (M.U., T.Y., Y.A.), Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuo-ku, Kumamoto 860-8556, Japan; and Department of Central Radiology, Kumamoto University Hospital, Kumamoto, Japan (T.E.).

Yukio Ando (Y)

Departments of Diagnostic Radiology (S.O., T.N., M.K., D.U., Y.N., Y.Y.), Medical Physics (Y.F.), Cardiology (S.T., K.T.), and Neurology (M.U., T.Y., Y.A.), Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuo-ku, Kumamoto 860-8556, Japan; and Department of Central Radiology, Kumamoto University Hospital, Kumamoto, Japan (T.E.).
ORCID: 0000-0001-7115-9105

Yasuyuki Yamashita (Y)

Departments of Diagnostic Radiology (S.O., T.N., M.K., D.U., Y.N., Y.Y.), Medical Physics (Y.F.), Cardiology (S.T., K.T.), and Neurology (M.U., T.Y., Y.A.), Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuo-ku, Kumamoto 860-8556, Japan; and Department of Central Radiology, Kumamoto University Hospital, Kumamoto, Japan (T.E.).
ORCID: 0000-0002-2905-1093

Classifications MeSH