Transcatheter Mitral Valve Repair and Replacement: Current Evidence for Intervention and the Role of CT in Preprocedural Planning-A Review for Radiologists and Cardiologists Alike.


Journal

Radiology. Cardiothoracic imaging
ISSN: 2638-6135
Titre abrégé: Radiol Cardiothorac Imaging
Pays: United States
ID NLM: 101748663

Informations de publication

Date de publication:
Feb 2020
Historique:
received: 07 06 2019
revised: 05 09 2019
accepted: 26 09 2019
entrez: 29 3 2021
pubmed: 30 3 2021
medline: 30 3 2021
Statut: epublish

Résumé

The mitral valve is a complex structure with a three-dimensional saddle shape annulus. Mitral regurgitation occurs from leaflet coaptation failure that is either primary (a problem with the leaflets) or secondary (chamber dilatation in the setting of cardiomyopathy). There has been an increase in focus on transcatheter mitral valve interventions, for both mitral repair and replacement. These technologies have rapidly developed to provide treatment for a substantial number of patients with severe symptomatic mitral regurgitation who are at too high of a risk to undergo open heart surgery. CT assessment of the mitral valve has developed with equal rapidity, with regard to preprocedural planning for transcatheter therapies. This review will provide an overview of mitral valve anatomy, an update on the current transcatheter repair and replacement therapies, as well as a focused overview of the role of multislice CT in mitral assessment prior to intervention. © RSNA, 2020.

Identifiants

pubmed: 33778537
doi: 10.1148/ryct.2020190106
pmc: PMC7977770
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

e190106

Informations de copyright

2020 by the Radiological Society of North America, Inc.

Déclaration de conflit d'intérêts

Disclosures of Conflicts of Interest: P.M. disclosed no relevant relationships. M.A. disclosed no relevant relationships. A.L.H. disclosed no relevant relationships. P.B. Activities related to the present article: disclosed no relevant relationships. Activities not related to the present article: consultant for Tendyne/Abbott Vascular, Edwards Lifesciences, Neovasc, and Circle Cardiovascular Imaging. Other relationships: provides CT Core laboratory services (University of British Columbia) for Tendyne/Abbott Vascular, Edwards Lifesciences, Medtronic, and Neovasc without direct compensation. J.L. Activities related to the present article: disclosed no relevant relationships. Activities not related to the present article: consultant for Circle CVI, HeartFlow, and UBC; has grant contracts with Edwards Lifesciences, Medtronic, Abbott, Neovasc, and research support from Edwards and GE Healthcare; has stock options in Circle CVI and HeartFlow. Other relationships: disclosed no relevant relationships.

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Auteurs

Paul Maggiore (P)

Centre for Heart Valve Innovation, St Paul's Hospital, University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6.

Malcolm Anastasius (M)

Centre for Heart Valve Innovation, St Paul's Hospital, University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6.

Alex L Huang (AL)

Centre for Heart Valve Innovation, St Paul's Hospital, University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6.

Philipp Blanke (P)

Centre for Heart Valve Innovation, St Paul's Hospital, University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6.

Jonathon Leipsic (J)

Centre for Heart Valve Innovation, St Paul's Hospital, University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6.

Classifications MeSH