Acid-Ion Sensing Channel 1a Deletion Reduces Chronic Brain Damage and Neurological Deficits after Experimental Traumatic Brain Injury.

Acid Sensing Ion Channels / deficiency Animals Brain Damage, Chronic / etiology Brain Injuries, Traumatic / complications Disease Models, Animal Male Mice Mice, Transgenic Motor Activity
animal studies brain edema cognitive function controlled cortical impact traumatic brain injury

Journal

Journal of neurotrauma
ISSN: 1557-9042
Titre abrégé: J Neurotrauma
Pays: United States
ID NLM: 8811626

Informations de publication

Date de publication:
01 06 2021
Historique:
pubmed: 30 3 2021
medline: 3 2 2022
entrez: 29 3 2021
Statut: ppublish

Résumé

Traumatic brain injury (TBI) causes long-lasting neurodegeneration and cognitive impairments; however, the underlying mechanisms of these processes are not fully understood. Acid-sensing ion channels 1a (ASIC1a) are voltage-gated Na

Identifiants

DOI: 10.1089/neu.2020.7568 PMID: 33779289
pubmed: 33779289
doi: 10.1089/neu.2020.7568
doi:

Substances chimiques

ASIC1 protein, mouse 0
Acid Sensing Ion Channels 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1572-1584

Auteurs

Shiqi Cheng (S)

Institute for Stroke and Dementia Research, Munich University Hospital, Munich, Germany.
Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.

Xiang Mao (X)

Institute for Stroke and Dementia Research, Munich University Hospital, Munich, Germany.
Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.

Xiangjiang Lin (X)

Institute for Stroke and Dementia Research, Munich University Hospital, Munich, Germany.
Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.

Antonia Wehn (A)

Institute for Stroke and Dementia Research, Munich University Hospital, Munich, Germany.
Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.

Senbin Hu (S)

Institute for Stroke and Dementia Research, Munich University Hospital, Munich, Germany.
Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.

Uta Mamrak (U)

Institute for Stroke and Dementia Research, Munich University Hospital, Munich, Germany.
Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.

Igor Khalin (I)

Institute for Stroke and Dementia Research, Munich University Hospital, Munich, Germany.
Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.

Maria Wostrack (M)

Department of Neurosurgery, Technical University Munich, Munich, Germany.

Florian Ringel (F)

Department of Neurosurgery, University Medical Center Mainz, Mainz, Germany.

Nikolaus Plesnila (N)

Institute for Stroke and Dementia Research, Munich University Hospital, Munich, Germany.
Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.

Nicole A Terpolilli (NA)

Institute for Stroke and Dementia Research, Munich University Hospital, Munich, Germany.
Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
Department of Neurosurgery, Munich University Hospital, Munich, Germany.

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de tissu nerveux › Canaux ioniques sensibles à l'acidité › Acid-Ion Sensing Channel 1a Deletion Reduces...
questionsmedicales.fr › Eucaryotes › Animaux › Acid-Ion Sensing Channel 1a Deletion Reduces...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Caractéristiques de la maladie › Maladie chronique › Souffrance cérébrale chronique › Acid-Ion Sensing Channel 1a Deletion Reduces...
questionsmedicales.fr › Plaies et blessures › Traumatismes du système nerveux › Traumatismes cranioencéphaliques › Lésions encéphaliques › Lésions traumatiques de l'encéphale › Acid-Ion Sensing Channel 1a Deletion Reduces...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › Modèles animaux de maladie humaine › Acid-Ion Sensing Channel 1a Deletion Reduces...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Acid-Ion Sensing Channel 1a Deletion Reduces...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Acid-Ion Sensing Channel 1a Deletion Reduces...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système locomoteur › Mouvement › Activité motrice › Acid-Ion Sensing Channel 1a Deletion Reduces...