Association between apathy and satisfaction with meaningful activities in older adults with mild cognitive impairment: A population-based cross-sectional study.


Journal

International journal of geriatric psychiatry
ISSN: 1099-1166
Titre abrégé: Int J Geriatr Psychiatry
Pays: England
ID NLM: 8710629

Informations de publication

Date de publication:
07 2021
Historique:
received: 02 03 2021
accepted: 21 03 2021
pubmed: 1 4 2021
medline: 9 7 2021
entrez: 31 3 2021
Statut: ppublish

Résumé

This cross-sectional study aimed to clarify the relationship between apathy, meaningful activities, and satisfaction with such activities of older adults with mild cognitive impairment (MCI). We analyzed 235 older adults with MCI (≥65 years, mean age: 76.9 ± 6.4 years, women: 63.4%) who participated in a community-based health check survey (Tarumizu Study 2018). MCI was defined as at least 1.5 SD below the reference threshold (age- and education-adjusted score) on one or more of the computerized cognitive test including memory, attention, executive functions, and processing speed. Apathy symptoms were assessed using three of the 15 items of Geriatric Depression Scale. Participants selected meaningful activities from the 95 activities of the Aid for Decision-Making in Occupation Choice and evaluated their satisfaction and performance. Apathy in MCI was prevalent by 23.8%. The categories of meaningful activities revealed no difference, with, or without apathy. Logistic regression analysis showed that activity satisfaction was significantly associated with apathy after adjusting for age, sex, education, instrumental activities of daily living, depressive symptoms, and MCI subtype (OR, 0.62; 95% CI, 0.44-0.88, p = 0.008). Satisfaction with the activities that are deemed meaningful is associated with apathy among community-dwelling older adults with MCI.

Identifiants

pubmed: 33786884
doi: 10.1002/gps.5544
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1065-1074

Informations de copyright

© 2021 John Wiley & Sons Ltd.

Références

Sosa-Ortiz AL, Acosta-Castillo I, Prince MJ. Epidemiology of dementias and Alzheimer's disease. Archives Med Res. 2012;43:600-608.
Janoutová J, Šerý O, Hosák L, Janout V. Is mild cognitive impairment a precursor of Alzheimer's disease? Short review. Cent Eur J Publ Health. 2015;23:365-367.
Kume Y, Takahashi T, Itakura Y, et al. Characteristics of mild cognitive impairment in northern Japanese community-dwellers from the ORANGE registry. Jcm. 2019;8:1937.
Winblad B, Palmer K, Kivipelto M, et al. Mild cognitive impairment - beyond controversies, towards a consensus: report of the international working group on mild cognitive impairment. J Intern Med. 2004;256:240-246.
Luis CA, Loewenstein DA, Acevedo A, Barker WW, Duara R. Mild cognitive impairment: directions for future research. Neurology. 2003;61:438-444.
Koyanagi A, Oh H, Vancampfort D, et al. Perceived stress and mild cognitive impairment among 32,715 community-dwelling older adults across six low- and middle-income countries. Gerontology. 2019;65:155-163.
Makizako H, Shimada H, Doi T, et al. Comorbid mild cognitive impairment and depressive symptoms predict future dementia in community older adults: a 24-month follow-up longitudinal study. J Alzheimers Dis. 2016;54:1473-1482.
Manly JJ, Tang M-X, Schupf N, Stern Y, Vonsattel J-PG, Mayeux R. Frequency and course of mild cognitive impairment in a multiethnic community. Ann Neurol. 2008;63:494-506.
Mitchell AJ, Shiri-Feshki M. Rate of progression of mild cognitive impairment to dementia - meta-analysis of 41 robust inception cohort studies. Acta Psychiatr Scand. 2009;119:252-265.
Zhao Q-F, Tan L, Wang H-F, et al. The prevalence of neuropsychiatric symptoms in Alzheimer's disease: systematic review and meta-analysis. J Affect Disord. 2016;190:264-271.
Siafarikas N, Selbaek G, Fladby T, Šaltytė Benth J, Auning E, Aarsland D. Frequency and subgroups of neuropsychiatric symptoms in mild cognitive impairment and different stages of dementia in Alzheimer's disease. Int Psychogeriatr. 2018;30:103-113.
Marin RS. Apathy: a neuropsychiatric syndrome. J Neuropsychiatry Clin Neurosci. 1991;3:243-254.
Levy R, Dubois B. Apathy and the functional anatomy of the prefrontal cortex-basal ganglia circuits. Cerebr Cortex. 2006;16:916-928.
Robert P, Lanctôt KL, Agüera-Ortiz L, et al. Is it time to revise the diagnostic criteria for apathy in brain disorders? The 2018 international consensus group. Eur Psychiatr. 2018;54:71-76.
Köhler CA, Magalhaes TF, Oliveira JM, et al. Neuropsychiatric disturbances in mild cognitive impairment (MCI): a systematic review of population-based studies. Curr Alzheimer Res. 2016;13:1066-1082.
Richard E, Schmand B, Eikelenboom P, et al. Symptoms of apathy are associated with progression from mild cognitive impairment to Alzheimer's disease in non-depressed subjects. Dement Geriatr Cognit Disord. 2012;33:204-209.
Starkstein SE, Leentjens AFG. The nosological position of apathy in clinical practice. J Neurol, Neurosurg & Psychiatry. 2008;79:1088-1092.
Ruthirakuhan M, Herrmann N, Vieira D, Gallagher D, Lanctôt KL. The roles of apathy and depression in predicting alzheimer disease: a longitudinal analysis in older adults with mild cognitive impairment. Am J Geriatric Psychiatry. 2019;27:873-882.
Ma L. Depression, anxiety, and apathy in mild cognitive impairment: current perspectives. Front Aging Neurosci. 2020;12:9.
Palmer K, Di Iulio F, Varsi AE, et al. Neuropsychiatric predictors of progression from amnestic-mild cognitive impairment to Alzheimer's disease: the role of depression and apathy. Jad. 2010;20:175-183.
Rozzini L, Chilovi BV, Trabucchi M, Padovani A. Depression is unrelated to conversion to dementia in patients with mild cognitive impairment. Arch Neurol. 2005;62:505-506.
Zhao J, Jin X, Chen B, et al. Apathy symptoms increase the risk of dementia conversion: a case-matching cohort study on patients with post-stroke mild cognitive impairment in China. Psychogeriatrics. 2021;21:149. https://doi.org/10.1111/psyg.12634
Mumba MN, Nacarrow AF, Cody S, et al. Intensity and type of physical activity predicts depression in older adults. Aging Ment Health. 2020;25:1-8.
Mackenzie CS, Abdulrazaq S. Social engagement mediates the relationship between participation in social activities and psychological distress among older adults. Aging Ment Health. 2021;25:299-305.
Lampinen P, Heikkinen R-L, Kauppinen M, Heikkinen E. Activity as a predictor of mental well-being among older adults. Aging Ment Health. 2006;10:454-466.
Tuijt R, Leung P, Profyri E, Orgeta V. Development and preliminary validation of the meaningful and enjoyable activities scale ( MEAS ) in mild dementia. Int J Geriatr Psychiatr. 2020;35:944-952.
Maruta M, Makizako H, Ikeda Y, et al. Associations between depressive symptoms and satisfaction with meaningful activities in community-dwelling Japanese older adults. J Clin Med. 2020;9:795.
World Health Organization. Active Ageing: A Policy Framework; 2002. https://apps.who.int/iris/bitstream/handle/10665/67215/WHO_NMH_NPH_02.8.pdf. Accessed September 30, 2020.
Oh A, Gan S, Boscardin WJ, et al. Engagement in meaningful activities among older adults with disability, dementia, and depression. JAMA Intern Med. 2021:e207492.
Moyers PA. The guide to occupational therapy practice. Am J Occup Ther. 1999;53:247-322.
National Institute for Health and Care Excellence. Mental Wellbeing of Older People in Care Homes; 2013. https://www.nice.org.uk/guidance/qs50/resources/mental-wellbeing-of-older-people-in-care-homes-pdf-2098720457413. Accessed February 14, 2021.
Fernández-ballesteros R, Dolores Zamarrón M, Angel Ruíz M. The contribution of socio-demographic and psychosocial factors to life satisfaction. Ageing Soc. 2001;21:25-43.
Lomranz J, Bergman S, Eyal N, Shmotkin D. Indoor and outdoor activities of aged women and men as related to depression and well-being. Int J Aging Hum Dev. 1988;26:303-314.
Tomori K, Saito Y, Nagayama H, et al. Reliability and validity of individualized satisfaction score in aid for decision-making in occupation choice. Disabil Rehabilitation. 2013;35:113-117.
Barton C, Ketelle R, Merrilees J, Miller B. Non-pharmacological management of behavioral symptoms in frontotemporal and other dementias. Curr Neurol Neurosci Rep. 2016;16:14.
Lu YY-F, Bakas T, Yang Z, Weaver MT, Austrom MG, Haase JE. Feasibility and effect sizes of theRevised daily engagement of meaningful activities interventionfor individuals with mild cognitive impairment and their caregivers. J Gerontol Nurs. 2016;42:45-58.
Brodaty H, Burns K. Nonpharmacological management of apathy in dementia: a systematic review. Am J Geriatric Psychiatry. 2012;20:549-564.
Theleritis C, Siarkos K, Katirtzoglou E, Politis A. Pharmacological and nonpharmacological treatment for apathy in alzheimer disease. J Geriatr Psychiatr Neurol. 2017;30:26-49.
Black BS, Johnston D, Rabins PV, Morrison A, Lyketsos C, Samus QM. Unmet needs of community-residing persons with dementia and their informal caregivers: findings from the maximizing independence at home study. J Am Geriatr Soc. 2013;61:2087-2095.
Albert MS, DeKosky ST, Dickson D, et al. The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimer's Dementia. 2011;7:270-279.
Kume Y, Takahashi T, Itakura Y, et al. Characteristics of mild cognitive impairment in northern Japanese community-dwellers from the ORANGE registry. J Clin Med. 2019;8:1937.
Johnston D, Samus QM, Morrison A, et al. Identification of community-residing individuals with dementia and their unmet needs for care. Int J Geriatr Psychiatr. 2011;26:292-298.
Makizako H, Shimada H, Park H, et al. Evaluation of multidimensional neurocognitive function using a tablet personal computer: test-retest reliability and validity in community-dwelling older adults. Geriatr Gerontol Int. 2013;13:860-866.
Shimada H, Makizako H, Park H, Doi T, Lee S. Validity of the national center for Geriatrics and gerontology-functional assessment tool and mini-mental state examination for detecting the incidence of dementia in older Japanese adults. Geriatr Gerontol Int. 2017;17:2383-2388.
Bae S, Shimada H, Lee S, et al. The relationships between components of metabolic syndrome and mild cognitive impairment subtypes: a cross-sectional study of Japanese older adults. J Alzheimers Dis. 2017;60:913-921.
Ligthart SA, Richard E, Fransen NL, et al. Association of vascular factors with apathy in community-dwelling elderly individuals. Arch Gen Psychiatr. 2012;69:636-642.
van der Mast RC, Vinkers DJ, Stek ML, et al. Vascular disease and apathy in old age. The Leiden 85-Plus Study. Int J Geriatr Psychiatr. 2008;23:266-271.
van Dalen JW, Van Wanrooij LL, Moll van Charante EP, Richard E, van Gool WA. Apathy is associated with incident dementia in community-dwelling older people. Neurology. 2018;90:e82-e89.
Eurelings LSM, Ligthart SA, van Dalen JW, Moll van Charante EP, van Gool WA, Richard E. Apathy is an independent risk factor for incident cardiovascular disease in the older individual: a population-based cohort study. Int J Geriatr Psychiatr. 2014;29:454-463.
Bertens AS, Moonen JEF, de Waal MWM, et al. Validity of the three apathy items of the Geriatric Depression Scale (GDS-3A) in measuring apathy in older persons. Int J Geriatr Psychiatr. 2017;32:421-428.
Adams KB, Matto HC, Sanders S. Confirmatory factor analysis of the Geriatric Depression Scale. Gerontologist. 2004;44:818-826.
Tomori K, Uezu S, Kinjo S, Ogahara K, Nagatani R, Higashi T. Utilization of the iPad application: aid for decision-making in occupation choice. Occup Ther Int. 2012;19:88-97.
Levack W, Tomori K, Takahashi K, Sherrington AJ. Development of an English-language version of a Japanese iPad application to facilitate collaborative goal setting in rehabilitation: a Delphi study and field test. BMJ Open. 2018;8:e018908.
Nagayama H, Tomori K, Ohno K, et al. Effectiveness and cost-effectiveness of occupation-based occupational therapy using the aid for decision making in occupation choice (ADOC) for older residents: pilot cluster randomized controlled trial. PLoS One. 2016;11:e0150374.
Muangpaisan W, Intalapaporn S, Assantachai P. Neuropsychiatric symptoms in the community-based patients with mild cognitive impairment and the influence of demographic factors. Int J Geriatr Psychiatr. 2008;23:699-703.
Apostolova LG, Di LJ, Duffy EL, et al. Risk factors for behavioral abnormalities in mild cognitive impairment and mild Alzheimer's disease. Dement Geriatr Cognit Disord. 2014;37:315-326.
Iwasa H, Masui Y, Inagaki H, et al. Assessing competence at a higher level among older adults: development of the Japan Science and Technology Agency Index of Competence (JST-IC). Aging Clin Exp Res. 2018;30:383-393.
Iwasa H, Masui Y, Inagaki H, et al. Development of the Japan science and Technology agency Index of competence to assess functional capacity in older adults: conceptual definitions and preliminary items. Gerontol Geriatr Med. 2015;1. 2333721415609490.
Rosenberg PB, Mielke MM, Appleby B, Oh E, Leoutsakos J-M, Lyketsos CG. Neuropsychiatric symptoms in MCI subtypes: the importance of executive dysfunction. Int J Geriatr Psychiatr. 2011;26:364-372.
Montoya-Murillo G, Ibarretxe-Bilbao N, Peña J, Ojeda N. The impact of apathy on cognitive performance in the elderly. Int J Geriatr Psychiatr. 2019;34:657-665.
Tumati S, Opmeer EM, Marsman JC, et al. Lower choline and myo-inositol in temporo-parietal cortex is associated with apathy in amnestic MCI. Front Aging Neurosci. 2018;10:106.
Franco MR, Tong A, Howard K, et al. Older people's perspectives on participation in physical activity: a systematic review and thematic synthesis of qualitative literature. Br J Sports Med. 2015;49:1268-1276.
Stubbs B, Eggermont L, Soundy A, Probst M, Vandenbulcke M, Vancampfort D. What are the factors associated with physical activity (PA) participation in community dwelling adults with dementia? A systematic review of PA correlates. Archives Gerontol Geriatr. 2014;59:195-203.
Ginsberg TB, Powell L, Emrani S, et al. Instrumental activities of daily living, neuropsychiatric symptoms, and neuropsychological impairment in mild cognitive impairment. J Am Osteopath Assoc. 2019;119:96-101.
Zahodne LB, Tremont G. Unique effects of apathy and depression signs on cognition and function in amnestic mild cognitive impairment. Int J Geriatr Psychiatr. 2013;28:50-56.
Law M, Steinwender S, Leclair L. Occupation, health and well-being. Can J Occup Ther. 1998;65:81-91.
Eakman AM, Eklund M. The relative impact of personality traits, meaningful occupation and occupational value on meaning in life and life satisfaction. J Occup Sci. 2012;19:165-177.
Clark FA, Parham D, Carlson ME, et al. Occupational science: academic innovation in the service of occupational therapy's future. Am J Occup Ther. 1991;45:300-310.
Krause N. Stressors arising in highly valued roles, meaning in life, and the physical health status of older adults. J Gerontol Ser B Psychol Sci Soc Sci. 2004;59:S287-S297.
O'Connor BP, Vallerand RJ. Psychological adjustment variables as predictors of mortality among nursing home residents. Psychol Aging. 1998;13:368-374.
Tierney SM, Woods SP, Weinborn M, Bucks RS. Real-world implications of apathy among older adults: independent associations with activities of daily living and quality of life. J Clin Exp Neuropsychol. 2018;40:895-903.
Groeneweg-Koolhoven I, de Waal MWM, van der Weele GM, Gussekloo J, van der Mast RC. Quality of life in community-dwelling older persons with apathy. Am J Geriatric Psychiatry. 2014;22:186-194.
Yeager CA, Hyer L. Apathy in dementia: relations with depression, functional competence, and quality of life. Psychol Rep. 2008;102:718-722.
Jacus JP. Awareness, apathy, and depression in Alzheimer's disease and mild cognitive impairment. Brain Behav 2017;7:e00661.
Horning SM, Melrose R, Sultzer D. Insight in Alzheimer's disease and its relation to psychiatric and behavioral disturbances. Int J Geriatr Psychiatr. 2014;29:77-84.
Boyle PA, Buchman AS, Barnes LL, Bennett DA. Effect of a purpose in life on risk of incident Alzheimer disease and mild cognitive impairment in community-dwelling older persons. Arch Gen Psychiatr. 2010;67:304-310.
Clarke DE, Ko JY, Kuhl EA, van Reekum R, Salvador R, Marin RS. Are the available apathy measures reliable and valid? A review of the psychometric evidence. J Psychosomatic Res. 2011;70:73-97.
Ceïde ME, Warhit A, Ayers EI, Kennedy G, Verghese J. Apathy and the risk of predementia syndromes in community-dwelling older adults. J Gerontol B Psychol Sci Soc Sci. 2020;75:1443-1450.

Auteurs

Michio Maruta (M)

Department of Rehabilitation, Medical Corporation, Sanshukai, Okatsu Hospital, Kagoshima, Japan.
Doctoral Program of Clinical Neuropsychiatry, Graduate School of Health Science, Kagoshima University, Kagoshima, Japan.

Hyuma Makizako (H)

Department of Physical Therapy, School of Health Sciences, Faculty of Medicine, Kagoshima University, Kagoshima, Japan.

Yuriko Ikeda (Y)

Department of Clinical Neuropsychiatry, Graduate School of Health Science, Kagoshima University, Kagoshima, Japan.

Hironori Miyata (H)

Doctoral Program of Clinical Neuropsychiatry, Graduate School of Health Science, Kagoshima University, Kagoshima, Japan.

Atsushi Nakamura (A)

Doctoral Program of Clinical Neuropsychiatry, Graduate School of Health Science, Kagoshima University, Kagoshima, Japan.

Gwanghee Han (G)

Department of Neuropsychiatry, Kumamoto University Hospital, Kumamoto, Japan.

Suguru Shimokihara (S)

Department of Rehabilitation, Minamikagoshima SAKURA Hospital, Kagoshima, Japan.

Keiichiro Tokuda (K)

Department of Rehabilitation, Medical Corporation, Gyokusyokai, Kirameki Terrace Healthcare Hospital, Kagoshima, Japan.

Takuro Kubozono (T)

Department of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.

Mitsuru Ohishi (M)

Department of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.

Takayuki Tabira (T)

Department of Clinical Neuropsychiatry, Graduate School of Health Science, Kagoshima University, Kagoshima, Japan.

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