Simultaneously acquired PET and ASL imaging biomarkers may be helpful in differentiating progression from pseudo-progression in treated gliomas.
Glioma
Magnetic resonance imaging
Perfusion, fluorodopa F 18
Prospective studies
Journal
European radiology
ISSN: 1432-1084
Titre abrégé: Eur Radiol
Pays: Germany
ID NLM: 9114774
Informations de publication
Date de publication:
Oct 2021
Oct 2021
Historique:
received:
19
10
2020
accepted:
29
01
2021
revised:
21
12
2020
pubmed:
1
4
2021
medline:
23
9
2021
entrez:
31
3
2021
Statut:
ppublish
Résumé
The aim of this work was investigating the methods based on coupling cerebral perfusion (ASL) and amino acid metabolism ([ Images were acquired using a 3-T PET/MR system, on a prospective cohort of patients addressed for possible glioma progression. Data were preprocessed with statistical parametric mapping (SPM), including registration on T1-weighted images, spatial and intensity normalization, and tumor segmentation. As index tests, tumor isocontour maps of [ Fifty-eight patients with unilateral treated glioma were included (34 progressions and 24 pseudo-progressions). The tumor isocontour maps and T-maps showed the highest specificity (100%) and sensitivity (94.1%) for ASL and [ Tumor isocontour T-maps and combined analysis of CBF and [ • Applied separately, MRI and PET imaging modalities may be insufficient to characterize the brain glioma post-therapeutic profile. • Combined ASL and [
Identifiants
pubmed: 33787971
doi: 10.1007/s00330-021-07732-0
pii: 10.1007/s00330-021-07732-0
doi:
Substances chimiques
Biomarkers
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
7395-7405Informations de copyright
© 2021. European Society of Radiology.
Références
Ricard D, Idbaih A, Ducray F, Lahutte M, Hoang-Xuan K, Delattre JY (2012) Primary brain tumours in adults. Lancet Lond Engl 379:1984–1996
Klobukowski L, Falkov A, Chelimo C, Fogh SE (2018) A retrospective review of re-irradiating patients’ recurrent high-grade gliomas. Clin Oncol (R Coll Radiol). https://doi.org/10.1016/j.clon.2018.05.004
Thust SC, Heiland S, Falini A et al (2018) Glioma imaging in Europe: a survey of 220 centres and recommendations for best clinical practice. Eur Radiol 28:3306–3317
pubmed: 29536240
pmcid: 6028837
Kumar AJ, Leeds NE, Fuller GN et al (2000) Malignant gliomas: MR imaging spectrum of radiation therapy- and chemotherapy-induced necrosis of the brain after treatment. Radiology 217:377–384
pubmed: 11058631
Mullins ME, Barest GD, Schaefer PW et al (2005) Radiation necrosis versus glioma recurrence: conventional MR imaging clues to diagnosis. AJNR Am J Neuroradiol 26:1967–1972
pubmed: 16155144
pmcid: 8148818
Aronen HJ, Gazit IE, Louis DN et al (1994) Cerebral blood volume maps of gliomas: comparison with tumor grade and histologic findings. Radiology 191:41–51
pubmed: 8134596
Law M, Yang S, Wang H et al (2003) Glioma grading: sensitivity, specificity, and predictive values of perfusion MR imaging and proton MR spectroscopic imaging compared with conventional MR imaging. AJNR Am J Neuroradiol 24:1989–1998
pubmed: 14625221
pmcid: 8148904
Mabray MC, Barajas RF, Cha S (2015) Modern brain tumor imaging. Brain Tumor Res Treat 3:8–23
pubmed: 25977902
pmcid: 4426283
Rossi A, Gandolfo C, Morana G, Severino M, Garrè ML, Cama A (2010) New MR sequences (diffusion, perfusion, spectroscopy) in brain tumours. Pediatr Radiol 40:999–1009
pubmed: 20432019
Haller S, Zaharchuk G, Thomas DL, Lovblad KO, Barkhof F, Golay X (2016) Arterial spin labeling perfusion of the brain: emerging clinical applications. Radiology 281:337–356
pubmed: 27755938
Galldiks N, Stoffels G, Ruge MI et al (2013) Role of O-(2-18F-fluoroethyl)-L-tyrosine PET as a diagnostic tool for detection of malignant progression in patients with low-grade glioma. J Nucl Med 54:2046–2054
pubmed: 24159047
Pirotte BJM, Levivier M, Goldman S et al (2009) Positron emission tomography-guided volumetric resection of supratentorial high-grade gliomas: a survival analysis in 66 consecutive patients. Neurosurgery 64:471–481 discussion 481
pubmed: 19240609
Brandes AA, Tosoni A, Spagnolli F et al (2008) Disease progression or pseudoprogression after concomitant radiochemotherapy treatment: pitfalls in neurooncology. Neuro Oncol 10:361–367
pubmed: 18401015
pmcid: 2563059
Boscolo Galazzo I, Mattoli MV, Pizzini FB et al (2016) Cerebral metabolism and perfusion in MR-negative individuals with refractory focal epilepsy assessed by simultaneous acquisition of (18)F-FDG PET and arterial spin labeling. Neuroimage Clin 11:648–657
Storti SF, Boscolo Galazzo I, Del Felice A et al (2014) Combining ESI, ASL and PET for quantitative assessment of drug-resistant focal epilepsy. Neuroimage 102(Pt 1):49–59
Morana G, Piccardo A, Tortora D et al (2017) Grading and outcome prediction of pediatric diffuse astrocytic tumors with diffusion and arterial spin labeling perfusion MRI in comparison with 18F-DOPA PET. Eur J Nucl Med Mol Imaging 44:2084–2093
pubmed: 28752225
Alsop DC, Detre JA, Golay X et al (2015) Recommended implementation of arterial spin-labeled perfusion MRI for clinical applications: a consensus of the ISMRM perfusion study group and the European consortium for ASL in dementia. Magn Reson Med 73:102–116
pubmed: 24715426
Brett M, Leff AP, Rorden C, Ashburner J (2001) Spatial normalization of brain images with focal lesions using cost function masking. Neuroimage 14:486–500
Lim Y-M, Cho Y-W, Shamim S et al (2008) Usefulness of pulsed arterial spin labeling MR imaging in mesial temporal lobe epilepsy. Epilepsy Res 82:183–189
pubmed: 19041041
pmcid: 2597620
Chen W, Silverman DHS, Delaloye S et al (2006) 18F-FDOPA PET imaging of brain tumors: comparison study with 18F-FDG PET and evaluation of diagnostic accuracy. J Nucl Med 47:904–911
pubmed: 16741298
Louis DN, Ohgaki H, Wiestler OD et al (2007) The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 114:97–109
Komori T (2017) The 2016 WHO classification of tumours of the central nervous system: the major points of revision. Neurol Med Chir (Tokyo) 57:301–311
Bergamino M, Saitta L, Barletta L et al (2013) Measurement of blood-brain barrier permeability with t1-weighted dynamic contrast-enhanced MRI in brain tumors: a comparative study with two different algorithms. ISRN Neurosci 2013:905279
pubmed: 24959569
pmcid: 4045531
Dolui S, Vidorreta M, Wang Z et al (2017) Comparison of PASL, PCASL, and background-suppressed 3D PCASL in mild cognitive impairment. Hum Brain Mapp 38:5260–5273
pubmed: 28737289
pmcid: 5593784
Gai ND, Chou YY, Pham D, Butman JA (2017) Reduced distortion artifact whole brain CBF mapping using blip-reversed non-segmented 3D echo planar imaging with pseudo-continuous arterial spin labeling. Magn Reson Imaging 44:119–124
pubmed: 28867670
pmcid: 5885766
Lindner T, Ahmeti H, Juhasz J et al (2018) A comparison of arterial spin labeling and dynamic susceptibility perfusion imaging for resection control in glioblastoma surgery. Oncotarget 9:18570–18577
pubmed: 29719627
pmcid: 5915094
Galldiks N, Langen K-J, Holy R et al (2012) Assessment of treatment response in patients with glioblastoma using O-(2-18F-fluoroethyl)-L-tyrosine PET in comparison to MRI. J Nucl Med 53:1048–1057
pubmed: 22645298
Pafundi DH, Laack NN, Youland RS et al (2013) Biopsy validation of 18F-DOPA PET and biodistribution in gliomas for neurosurgical planning and radiotherapy target delineation: results of a prospective pilot study. Neuro Oncol 15:1058–1067
pubmed: 23460322
pmcid: 3714146
Furtner J, Bender B, Braun C et al (2014) Prognostic value of blood flow measurements using arterial spin labeling in gliomas. PLoS One 9:e99616
pubmed: 24911025
pmcid: 4049763
Salber D, Stoffels G, Pauleit D et al (2007) Differential uptake of O-(2-18F-fluoroethyl)-L-tyrosine, L-3H-methionine, and 3H-deoxyglucose in brain abscesses. J Nucl Med 48:2056–2062
pubmed: 18006612
Langen K-J, Bröer S (2004) Molecular transport mechanisms of radiolabeled amino acids for PET and SPECT. J Nucl Med 45:1435–1436
pubmed: 15347708
Gasparetto EL, Pawlak MA, Patel SH et al (2009) Posttreatment recurrence of malignant brain neoplasm: accuracy of relative cerebral blood volume fraction in discriminating low from high malignant histologic volume fraction. Radiology 250:887–896
pubmed: 19244052
Filss CP, Cicone F, Shah NJ, Galldiks N, Langen K-J (2017) Amino acid PET and MR perfusion imaging in brain tumours. Clin Transl Imaging 5:209–223
pubmed: 28680873
pmcid: 5487907
Wang Y-F, Hou B, Yang S-J et al (2016) Diagnostic significance of arterial spin labeling in the assessment of tumor grade in brain. J Cancer Res Ther 12:259–266
pubmed: 27072248
Kinahan PE, Fletcher JW (2010) Positron emission tomography-computed tomography standardized uptake values in clinical practice and assessing response to therapy. Semin Ultrasound CT MR 31:496–505
pubmed: 21147377
pmcid: 3026294