Effect of quantitative values on shortened acquisition duration in brain tumor

11C-methionine Acquisition duration SUVpeak Statistical noise

Journal

EJNMMI physics
ISSN: 2197-7364
Titre abrégé: EJNMMI Phys
Pays: Germany
ID NLM: 101658952

Informations de publication

Date de publication:
31 Mar 2021
Historique:
received: 12 12 2020
accepted: 18 03 2021
entrez: 31 3 2021
pubmed: 1 4 2021
medline: 1 4 2021
Statut: epublish

Résumé

The amount of signal decreases when the acquisition duration is shortened. However, it is not clear how this affects the quantitative values. This study aims to clarify the effect of acquisition time shortening in brain tumor PET/CT using This study was a retrospective analysis of 30 patients who underwent clinical SUVmax, MTV, and TNRmax showed the highest values due to the effects of statistical noise when the acquisition time was 1 min. These values were stable when the acquisition duration was > 6 min. SUVpeak and SUVmean showed mostly consistent values regardless of duration. SUVmax, MTV, and TNRmax are affected by acquisition time. If the acquisition duration was > 6 min, the fluctuation could be suppressed within 5% in these quantitative values. However, SUVpeak was suggested to be a robust index regardless of the acquisition duration.

Sections du résumé

BACKGROUND BACKGROUND
The amount of signal decreases when the acquisition duration is shortened. However, it is not clear how this affects the quantitative values. This study aims to clarify the effect of acquisition time shortening in brain tumor PET/CT using
METHOD METHODS
This study was a retrospective analysis of 30 patients who underwent clinical
RESULTS RESULTS
SUVmax, MTV, and TNRmax showed the highest values due to the effects of statistical noise when the acquisition time was 1 min. These values were stable when the acquisition duration was > 6 min. SUVpeak and SUVmean showed mostly consistent values regardless of duration.
CONCLUSIONS CONCLUSIONS
SUVmax, MTV, and TNRmax are affected by acquisition time. If the acquisition duration was > 6 min, the fluctuation could be suppressed within 5% in these quantitative values. However, SUVpeak was suggested to be a robust index regardless of the acquisition duration.

Identifiants

pubmed: 33788057
doi: 10.1186/s40658-021-00379-2
pii: 10.1186/s40658-021-00379-2
pmc: PMC8012475
doi:

Types de publication

Journal Article

Langues

eng

Pagination

34

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Auteurs

Masatoshi Morimoto (M)

Division of Social and Environmental Medicine, Graduate School of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa, 761-0793, Japan. m-mori@med.kagawa-u.ac.jp.
Department of Clinical Radiology, Kagawa University Hospital, Kita-gun, Kagawa, 761-0793, Japan. m-mori@med.kagawa-u.ac.jp.

Nobuyuki Kudomi (N)

Department of Medical Physics, Faculty of Medicine, Kagawa University, Kita-gun, Kagawa, 761-0793, Japan.

Yukito Maeda (Y)

Department of Clinical Radiology, Kagawa University Hospital, Kita-gun, Kagawa, 761-0793, Japan.

Takuya Kobata (T)

Department of Clinical Radiology, Kagawa University Hospital, Kita-gun, Kagawa, 761-0793, Japan.

Akihiro Oishi (A)

Department of Clinical Radiology, Kagawa University Hospital, Kita-gun, Kagawa, 761-0793, Japan.

Keisuke Matsumoto (K)

Department of Clinical Radiology, Kagawa University Hospital, Kita-gun, Kagawa, 761-0793, Japan.

Toshihide Monden (T)

Department of Clinical Radiology, Kagawa University Hospital, Kita-gun, Kagawa, 761-0793, Japan.

Takanobu Iwasaki (T)

Faculty of Health and Welfare, Tokushima Bunri University, 1314-1 Shido, Sanuki-city, Kagawa, 769-2193, Japan.

Katsuya Mitamura (K)

Department of Radiology, Faculty of Medicine, Kagawa University, Kita-gun, Kagawa, 761-0793, Japan.

Takashi Norikane (T)

Department of Radiology, Faculty of Medicine, Kagawa University, Kita-gun, Kagawa, 761-0793, Japan.

Yuka Yamamoto (Y)

Department of Radiology, Faculty of Medicine, Kagawa University, Kita-gun, Kagawa, 761-0793, Japan.

Yoshihiro Nishiyama (Y)

Department of Radiology, Faculty of Medicine, Kagawa University, Kita-gun, Kagawa, 761-0793, Japan.

Classifications MeSH