Assessment, prevalence, and correlates of frailty among middle-aged adults with HIV in rural Uganda.
Activities of Daily Living
/ psychology
Adult
Aged
Anti-HIV Agents
/ therapeutic use
Antiretroviral Therapy, Highly Active
Cross-Sectional Studies
Depression
/ complications
Exercise
/ physiology
Female
Frailty
/ complications
HIV Infections
/ complications
Humans
Male
Middle Aged
Neurocognitive Disorders
/ complications
Prevalence
Risk Factors
Rural Population
Surveys and Questionnaires
Uganda
/ epidemiology
ART
Frailty
Global Health
HIV
Neuropsychology
Uganda
Journal
Journal of neurovirology
ISSN: 1538-2443
Titre abrégé: J Neurovirol
Pays: United States
ID NLM: 9508123
Informations de publication
Date de publication:
06 2021
06 2021
Historique:
received:
16
10
2020
accepted:
09
03
2021
revised:
26
01
2021
pubmed:
1
4
2021
medline:
22
1
2022
entrez:
31
3
2021
Statut:
ppublish
Résumé
We investigated the prevalence and risk factors for frailty among people with HIV (PWH) in rural Uganda (n = 55, 47% male, mean age 44 years). Frailty was defined according to the Fried criteria with self-reported physical activity level replacing the Minnesota Leisure Time Activity Questionnaire. Alternate classifications for physical activity utilized were the sub-Saharan Africa Activity Questionnaire and the International Physical Activity Questionnaire. Eleven participants (19%) were frail. Frail participants were older (p < 0.001), less likely to be on antiretroviral therapy (p = 0.03), and had higher rates of depression (p < .001) and HIV-associated neurocognitive disorder (p = 0.003). Agreement between physical activity measures was sub-optimal. Prevalence of frailty was high among PWH in rural Uganda, but larger sample sizes and local normative data are needed.
Identifiants
pubmed: 33788138
doi: 10.1007/s13365-021-00969-x
pii: 10.1007/s13365-021-00969-x
doi:
Substances chimiques
Anti-HIV Agents
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
487-492Subventions
Organisme : NINDS NIH HHS
ID : L30 NS088658
Pays : United States
Organisme : NIAID NIH HHS
ID : P30 AI094189
Pays : United States
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