Light emitting diode-red light for reduction of post-surgical scarring: Results from a dose-ranging, split-face, randomized controlled trial.
low level light therapy
phototherapy
scarring
wound healing
Journal
Journal of biophotonics
ISSN: 1864-0648
Titre abrégé: J Biophotonics
Pays: Germany
ID NLM: 101318567
Informations de publication
Date de publication:
07 2021
07 2021
Historique:
revised:
19
03
2021
received:
26
02
2021
accepted:
29
03
2021
pubmed:
1
4
2021
medline:
13
8
2021
entrez:
31
3
2021
Statut:
ppublish
Résumé
Scarring has significant esthetic and functional consequences for patients. A need exists for anti-scarring therapeutics. Light emitting diode-red light (LED-RL) has been shown to modulate skin fibrosis. The aim of this study is to evaluate the safety and efficacy of LED-RL to reduce post-operative scarring. Cutaneous Understanding of Red-light Efficacy on Scarring was a randomized, mock-controlled, single-blind, dose-ranging, split-face phase II clinical trial. Starting 1 week post-surgery, patients received LED-RL irradiation and temperature-controlled mock therapy to incision sites at fluences of 160, 320 or 480 J/cm
Identifiants
pubmed: 33788987
doi: 10.1002/jbio.202100073
pmc: PMC8919713
mid: NIHMS1781274
doi:
Types de publication
Journal Article
Randomized Controlled Trial
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
e202100073Subventions
Organisme : NIGMS NIH HHS
ID : K23 GM117309
Pays : United States
Informations de copyright
© 2021 The Authors. Journal of Biophotonics published by Wiley-VCH GmbH.
Références
J Pathol. 2008 Jan;214(2):199-210
pubmed: 18161745
J Korean Med Sci. 2014 Jun;29(6):751-7
pubmed: 24932073
Aging Clin Exp Res. 2008 Jun;20(3):195-200
pubmed: 18594185
JAMA Dermatol. 2017 Mar 1;153(3):364
pubmed: 28273311
J Clin Aesthet Dermatol. 2018 Feb;11(2):21-27
pubmed: 29552272
Adv Wound Care (New Rochelle). 2015 Oct 1;4(10):607-614
pubmed: 26487979
Can J Ophthalmol. 2018 Feb;53(1):29-33
pubmed: 29426436
J Am Acad Dermatol. 2010 Dec;63(6):1006-10
pubmed: 20226568
Dermatol Surg. 2015 Jan;41(1):35-9
pubmed: 25485805
Dermatol Surg. 2018 Oct;44(10):1317-1322
pubmed: 29846344
J Invest Dermatol. 2012 Jul;132(7):1901-7
pubmed: 22318388
Ann Biomed Eng. 2012 Feb;40(2):516-33
pubmed: 22045511
J Biophotonics. 2019 May;12(5):e201800207
pubmed: 30182520
Skin Pharmacol Physiol. 2012;25(1):25-33
pubmed: 21912200
Adv Wound Care (New Rochelle). 2018 Feb 1;7(2):29-45
pubmed: 29392092
J Am Acad Dermatol. 2012 Jan;66(1):1-10; quiz 11-2
pubmed: 22177631
PLoS One. 2012;7(10):e47460
pubmed: 23077622
Semin Plast Surg. 2016 Aug;30(3):122-8
pubmed: 27478420
Eur J Dermatol. 2014 Jul-Aug;24(4):435-43
pubmed: 25141160
Dermatol Surg. 2014 Aug;40(8):825-31
pubmed: 25068544
Int J Dermatol. 2014 Aug;53(8):922-36
pubmed: 24697346
Plast Reconstr Surg. 2015 Mar;135(3):907-917
pubmed: 25719706
Dermatol Surg. 2014 Aug;40(8):817-24
pubmed: 25068543
Wound Repair Regen. 2009 Nov-Dec;17(6):763-71
pubmed: 19903300
J Eur Acad Dermatol Venereol. 2018 Jul;32(7):1099-1110
pubmed: 29419914
Lasers Surg Med. 2018 Jan;50(1):28-36
pubmed: 28815643
Aesthet Surg J. 2016 Jan;36(1):1-13
pubmed: 26578747
BMJ. 2003 Jan 11;326(7380):88-92
pubmed: 12521975
Photodiagnosis Photodyn Ther. 2010 Sep;7(3):183-8
pubmed: 20728843
Arch Dermatol Res. 2006 Apr;297(10):433-8
pubmed: 16528552
Skin Res Technol. 2010 Feb;16(1):38-54
pubmed: 20384882
Dermatol Surg. 2013 Aug;39(8):1167-70
pubmed: 23590233
Photochem Photobiol. 2008 Mar-Apr;84(2):450-62
pubmed: 18248499
Wound Repair Regen. 2011 Sep;19 Suppl 1:s32-7
pubmed: 21793964
Photodermatol Photoimmunol Photomed. 2010 Dec;26(6):330-2
pubmed: 21140993
Int J Oral Maxillofac Surg. 1994 Aug;23(4):232-6
pubmed: 7798696
J Biophotonics. 2020 Mar;13(3):e201960014
pubmed: 31483941
Dermatol Surg. 2015 Mar;41(3):307-20
pubmed: 25705949
J Clin Aesthet Dermatol. 2015 Jun;8(6):36-44
pubmed: 26155326
Adv Wound Care (New Rochelle). 2018 Feb 1;7(2):47-56
pubmed: 29392093
Lymphat Res Biol. 2017 Mar;15(1):70-76
pubmed: 28277926
Br J Dermatol. 2012 Feb;166(2):413-6
pubmed: 21848691
Gerontology. 2013;59(2):159-64
pubmed: 23108154
Lasers Surg Med. 2018 Jan 22;:
pubmed: 29356026
Plast Reconstr Surg. 2000 Apr;105(5):1591-9
pubmed: 10809086
Plast Reconstr Surg. 2008 May;121(5):1650-1658
pubmed: 18453989
Wound Repair Regen. 2007 Jul-Aug;15(4):497-504
pubmed: 17650093
J Biophotonics. 2016 Dec;9(11-12):1167-1179
pubmed: 27174640
Skin Res Technol. 2018 Aug;24(3):466-471
pubmed: 29405450
Am J Clin Dermatol. 2016 Jun;17(3):201-23
pubmed: 26894654
Int J Mol Sci. 2018 Mar 02;19(3):
pubmed: 29498630
Trials. 2019 Jul 15;20(1):432
pubmed: 31307501
Int J Cosmet Sci. 2018 Apr;40(2):134-140
pubmed: 29314077
J Plast Reconstr Aesthet Surg. 2008 Sep;61(9):1049-58
pubmed: 18617450
J Cosmet Dermatol. 2019 Jun;18(3):874-878
pubmed: 29935013
Nat Med. 2012 Jul 06;18(7):1028-40
pubmed: 22772564
Am J Pathol. 2006 Jun;168(6):1861-8
pubmed: 16723701
J Am Acad Dermatol. 2012 Jan;66(1):13-24; quiz 25-6
pubmed: 22177632