Evaluation of the Long-term Administration of Rifaximin for More than Three Years in the Treatment of Repeated and Recurrent Overt Hepatic Encephalopathy.
hyperammonemia
liver cirrhosis
overt hepatic encephalopathy
rifaximin
Journal
Internal medicine (Tokyo, Japan)
ISSN: 1349-7235
Titre abrégé: Intern Med
Pays: Japan
ID NLM: 9204241
Informations de publication
Date de publication:
2021
2021
Historique:
entrez:
1
4
2021
pubmed:
2
4
2021
medline:
15
4
2021
Statut:
ppublish
Résumé
The patient was a 65-year-old man with alcoholic liver cirrhosis who had been admitted to hospital 5 times for repeated and recurrent overt hepatic encephalopathy (HE) despite numerous therapies, including disaccharide, branched-chain amino acid (BCAA) formula, L-carnitine and zinc. After the additional administration of rifaximin (1,200 mg/day orally), his consciousness level was well controlled for 3 years without any adverse effects. The long-term administration of rifaximin may be useful and safe for managing recurrent overt HE, although the maintenance dosage and duration of rifaximin and safety should be evaluated in patients with ameliorated HE.
Identifiants
pubmed: 33790139
doi: 10.2169/internalmedicine.5793-20
pmc: PMC8079929
doi:
Substances chimiques
Amino Acids, Branched-Chain
0
Rifaximin
L36O5T016N
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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