Experimental Disease-Modifying Agents for Frontotemporal Lobar Degeneration.
C9orf72
GRN
MAPT
TDP-43
frontotemporal dementia
frontotemporal lobar degeneration
tau
therapy
Journal
Journal of experimental pharmacology
ISSN: 1179-1454
Titre abrégé: J Exp Pharmacol
Pays: New Zealand
ID NLM: 101530345
Informations de publication
Date de publication:
2021
2021
Historique:
received:
22
01
2021
accepted:
09
03
2021
entrez:
1
4
2021
pubmed:
2
4
2021
medline:
2
4
2021
Statut:
epublish
Résumé
Frontotemporal dementia is a clinically, genetically and pathologically heterogeneous neurodegenerative disorder, enclosing a wide range of different pathological entities, associated with the accumulation of proteins such as tau and TPD-43. Characterized by a high hereditability, mutations in three main genes,
Identifiants
pubmed: 33790662
doi: 10.2147/JEP.S262352
pii: 262352
pmc: PMC8005747
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
359-376Informations de copyright
© 2021 Giunta et al.
Déclaration de conflit d'intérêts
Dr Eino Solje reports grants from Orion Research Foundation, outside the submitted work. The authors report no other potential conflicts of interest for this work.
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