18F-FET PET/CT in Early Subventricular Zone Recurrence of Adult Glioblastoma.
Journal
Clinical nuclear medicine
ISSN: 1536-0229
Titre abrégé: Clin Nucl Med
Pays: United States
ID NLM: 7611109
Informations de publication
Date de publication:
01 06 2021
01 06 2021
Historique:
pubmed:
3
4
2021
medline:
21
5
2021
entrez:
2
4
2021
Statut:
ppublish
Résumé
Glioma stem cells (GSCs) are the source of tumor recurrence in glioblastoma and are capable of whole tumor regeneration once the treatment has concluded. Compelling evidence from the last decade suggests that GSC may arise from neural stem cells residing in the adult subventricular zone (SVZ). We report the findings of an 18F-FET PET/CT showing pathological uptake in SVZ with a tumor-background ratio of greater than 1.6, giving evidence for glioblastoma recurrence. This case highlights the particular attention to be paid to the SVZ given the possible development of GSC.
Identifiants
pubmed: 33795588
doi: 10.1097/RLU.0000000000003639
pii: 00003072-202106000-00015
doi:
Substances chimiques
(18F)fluoroethyltyrosine
1326R5J1IA
Tyrosine
42HK56048U
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
499-500Informations de copyright
Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.
Déclaration de conflit d'intérêts
Conflicts of interest and sources of funding: none declared.
Références
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