A Case Series of "Solitary Idiopathic Choroiditis" and Proposal of a Nomenclature Change to "Idiopathic Scleroma".

Ocular oncology Optical coherence tomography Solitary idiopathic choroiditis

Journal

Ocular oncology and pathology
ISSN: 2296-4681
Titre abrégé: Ocul Oncol Pathol
Pays: Switzerland
ID NLM: 101656139

Informations de publication

Date de publication:
Mar 2021
Historique:
received: 07 05 2020
accepted: 06 07 2020
entrez: 2 4 2021
pubmed: 3 4 2021
medline: 3 4 2021
Statut: ppublish

Résumé

To define the characteristics of solitary idiopathic choroiditis (SIC) in a consecutive series of patients and propose a nomenclature change to idiopathic scleroma. Electronic patient records were retrospectively interrogated to identify all patients diagnosed with SIC between 2002 and 2019 in a tertiary referral ophthalmic hospital in the United Kingdom. Thirty-four eyes of 34 patients were found to have SIC. The mean age at diagnosis was 48 years (range 24-78) and 23 patients (68%) were female. All lesions were located posterior to the equator, most frequently in the inferotemporal quadrant (13 eyes, 38%). The lesions had a mean largest basal diameter of 1.2 ± 0.4 disc diameters (range 0.5-2) and their distance to the optic disc had a mean of 1.2 ± 0.9 disc diameters (range 0-3.3). All lesions were intrascleral on enhanced depth imaging optical coherence tomography, demonstrating a hypo-reflective zone within the sclera, with an underlying hyper-reflective zone in some cases. No lesion enlarged or developed features consistent with active inflammation after a median follow-up time of 0.9 years (range 0-16.8). Optical coherence tomography shows SIC to be an intrascleral lesion. Furthermore, we found no evidence of any inflammatory component. A nomenclature change to idiopathic scleroma is appropriate to prevent unnecessary investigation.

Identifiants

pubmed: 33796517
doi: 10.1159/000509942
pii: oop-0007-0048
pmc: PMC7989809
doi:

Types de publication

Journal Article

Langues

eng

Pagination

48-53

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2020 by S. Karger AG, Basel.

Déclaration de conflit d'intérêts

The authors declare no disclosures or conflicts of interest.

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Auteurs

Emma Duignan (E)

Ophthalmology Department, Moorfields Eye Hospital, London, United Kingdom.

Roderick O'Day (R)

Ophthalmology Department, Moorfields Eye Hospital, London, United Kingdom.

Thomas Moloney (T)

Ophthalmology Department, Moorfields Eye Hospital, London, United Kingdom.

Waheeda Rahman (W)

Ophthalmology Department, Moorfields Eye Hospital, London, United Kingdom.

Bertil Damato (B)

Ophthalmology Department, Moorfields Eye Hospital, London, United Kingdom.
Nuffield Laboratory of Ophthalmology, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom.

Classifications MeSH