Temporal changes in epidemiological profile and fetal indications for late termination of pregnancy: a retrospective single-center study.


Journal

Archives of gynecology and obstetrics
ISSN: 1432-0711
Titre abrégé: Arch Gynecol Obstet
Pays: Germany
ID NLM: 8710213

Informations de publication

Date de publication:
10 2021
Historique:
received: 09 06 2020
accepted: 18 03 2021
pubmed: 3 4 2021
medline: 26 11 2021
entrez: 2 4 2021
Statut: ppublish

Résumé

To explore whether epidemiological shifts regarding reproduction and pregnancy have influenced the spectrum of indications for late termination of singleton pregnancies (TOP) above 17 weeks of gestation and to evaluate temporal changes in maternal demographics and fetal indications over the last 16 years. Retrospective single-center cohort study involving all late TOPs preceded by feticide between 1 January 2004 and 31 December 2019 at a tertiary referral hospital in Austria. Outcome variables were retrieved and a time trend assessed between two 8-year intervals (2004-2011 versus 2012-2019). Between January 2004 and December 2019, a total of 209 singleton pregnancies (50.7% male; 46.9% female fetuses, 2.4% no disclosed sex) were terminated medically at a median gestational age of 25 Population profile and indications for late TOPs followed by feticide remain unchanged over time.

Identifiants

pubmed: 33797606
doi: 10.1007/s00404-021-06042-6
pii: 10.1007/s00404-021-06042-6
pmc: PMC8429401
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

935-942

Informations de copyright

© 2021. The Author(s).

Références

Habiba M, Da Frè M, Taylor DJ et al (2009) Late termination of pregnancy: a comparison of obstetricians’ experience in eight European countries. BJOG Int J Obstet Gynaecol 116:1340–1349
doi: 10.1111/j.1471-0528.2009.02228.x
Strafgesetzbuch (2018) § 97 StGB Straflosigkeit des Schwangerschaftsabbruchs
Chervenak FA, Mccullough LB (2009) An ethically justified practical approach to offering, recommending, performing, and referring for induced abortion and feticide. Am J Obstet Gynecol 201(560):e561-566
Gissler M, Fronteira I, Jahn A et al (2012) Terminations of pregnancy in the European Union. BJOG Int J Obstet Gynaecol 119:324–332
doi: 10.1111/j.1471-0528.2011.03189.x
Cook RJ (2000) Developments in abortion laws. Comparative and international perspectives. Ann N Y Acad Sci 913:74–87
doi: 10.1111/j.1749-6632.2000.tb05163.x
Cook RJ, Dickens BM (1989) International developments in abortion laws: 1977–88. IPPF Med Bull 23:3–4
pubmed: 12315868
Centre for Reproductive Rights (2020) Wyrok Trybunału Konstytucyjnego z dnia 22 października 2020 r. sygn. akt K 1/20
Garne E, Khoshnood B, Loane M et al (2010) Termination of pregnancy for fetal anomaly after 23 weeks of gestation: a European register-based study. BJOG Int J Obstet Gynaecol 117:660–666
doi: 10.1111/j.1471-0528.2010.02531.x
Sunderam S, Kissin DM, Zhang Y et al. (2019) Assisted Reproductive Technology Surveillance—United States, 2016. Morbidity and mortality weekly report. Surveillance summaries (Washington, D.C, 2002) 68:1–23
Kocourková J, Šťastná A (2021) The realization of fertility intentions in the context of childbearing postponement: comparison of transitional and post-transitional populations. J Biosoc Sci 53:82–97
doi: 10.1017/S002193202000005X
Hartnett CS, Gemmill A (2020) Recent trends in U.S. childbearing intentions. Demography 57:2035–2045
doi: 10.1007/s13524-020-00929-w
Blumenfeld Z (2020) Possible impact of COVID-19 on fertility and assisted reproductive technologies. Fertil Steril 114:56–57
doi: 10.1016/j.fertnstert.2020.05.023
Hansen M, Kurinczuk JJ, Milne E et al (2013) Assisted reproductive technology and birth defects: a systematic review and meta-analysis. Hum Reprod Update 19:330–353
doi: 10.1093/humupd/dmt006
Davies MJ, Moore VM, Willson KJ et al (2012) Reproductive technologies and the risk of birth defects. N Engl J Med 366:1803–1813
doi: 10.1056/NEJMoa1008095
World Health Organization (2020) Classification of diseases (ICD). World Health Organization, Geneva
Stoll C, Alembik Y, Dott B et al (2002) Impact of prenatal diagnosis on livebirth prevalence of children with congenital anomalies. Ann Genet 45:115–121
doi: 10.1016/S0003-3995(02)01130-9
Julian-Reynier C, Philip N, Scheiner C et al (1994) Impact of prenatal diagnosis by ultrasound on the prevalence of congenital anomalies at birth in southern France. J Epidemiol Community Health 48:290–296
doi: 10.1136/jech.48.3.290
Corbacioglu A, Aslan H, Aydin S et al (2012) Trends in fetal indications for termination of pregnancy between 2002 and 2010 at a tertiary referral centre. J Turk Ger Gynecol Assoc 13:85–90
doi: 10.5152/jtgga.2012.09
Feldman N, Melcer Y, Hod E et al (2018) Termination of pregnancy due to fetal abnormalities performed after 32 weeks’ gestation: survey of 57 fetuses from a single medical center. J Maternal-fetal Neonatal Med 31:740–746
doi: 10.1080/14767058.2017.1297406
Melcer Y, Maymon R, Krajden Haratz K et al (2018) Termination of pregnancy due to fetal central nervous system abnormalities performed after 24 weeks’ gestation: survey of 57 fetuses from a single medical center. Arch Gynecol Obstet 298:551–559
doi: 10.1007/s00404-018-4836-z
Barel O, Vaknin Z, Smorgick N et al (2009) Fetal abnormalities leading to third trimester abortion: nine-year experience from a single medical center. Prenat Diagn 29:223–228
doi: 10.1002/pd.2188
Vaknin Z, Ben-Ami I, Reish O et al (2006) Fetal abnormalities leading to termination of singleton pregnancy: the 7-year experience of a single medical center. Prenat Diagn 26:938–943
doi: 10.1002/pd.1531
De Keersmaecker B, Claus F, De Catte L (2011) Imaging the fetal central nervous system. Facts Views Vis Obgyn 3:135–149
pubmed: 24753859 pmcid: 3991457
Statham H, Solomou W, Green J (2006) Late termination of pregnancy: law, policy and decision making in four English fetal medicine units. BJOG Int J Obstet Gynaecol 113:1402–1411
doi: 10.1111/j.1471-0528.2006.01144.x

Auteurs

Dana Anaïs Muin (DA)

Division of Fetomaternal Medicine, Department of Obstetrics and Gynecology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria. dana.muin@meduniwien.ac.at.

Patricia Otte (P)

Division of Fetomaternal Medicine, Department of Obstetrics and Gynecology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

Anke Scharrer (A)

Clinical Institute of Pathology, Medical University of Vienna, Vienna, Austria.

Gregor Kasprian (G)

Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.

Peter W Husslein (PW)

Division of Fetomaternal Medicine, Department of Obstetrics and Gynecology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

Herbert Kiss (H)

Division of Fetomaternal Medicine, Department of Obstetrics and Gynecology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

Dieter Bettelheim (D)

Division of Fetomaternal Medicine, Department of Obstetrics and Gynecology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH