Comparison of erectile function in patients with end-stage renal disease receiving haemodialysis and kidney transplantation.
IIEF-15
erectile dysfunction
haemodialysis
kidney transplant
Journal
Andrologia
ISSN: 1439-0272
Titre abrégé: Andrologia
Pays: Germany
ID NLM: 0423506
Informations de publication
Date de publication:
Jul 2021
Jul 2021
Historique:
received:
12
03
2021
accepted:
21
03
2021
pubmed:
3
4
2021
medline:
22
6
2021
entrez:
2
4
2021
Statut:
ppublish
Résumé
To investigate the frequency and risk factors of ED in haemodialysis patients (HDps) and kidney transplantation (KTx) recipients (KTxRs). HDps and KTxRs between the ages of 18-65 were compared in terms of ED. IEFF-15 (International Index of Erectile Function) score was used to evaluation of ED. Fifty-seven male HDps and 52 male KTxRs with a mean age of 45.6 ± 10.4 years were included in our study. DM, CAD, hyperlipidaemia, smoking and beta blocker use were higher HDps (p = 0.037, p < 0.001, p = 0.001, p = 0.001 and p = 0.031 respectively). There was no ED in five (8.8%) HDps and 27(51.9%) KTxRx. Severity of ED was significantly higher in HDps (p < 0.001). In multiple logistic regression analysis, KTx was found the most relevant associated factor with ED. KTxRs had decreased risk for ED (OR = 0.09, 95% CI 0.02-0.30, p < 0.001). ED is significantly more common in HDps than KTxRs. Known risk factors for ED, HT, DM, CAD, HL, smoking, obesity and beta-blocker use were not related to ED in the HDps and KTxRs, and the KTx was positively effective for ED in patients undergoing renal replacement therapy.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e14068Informations de copyright
© 2021 Wiley-VCH GmbH.
Références
Al Khallaf, H. H. (2010). Analysis of sexual functions in male nondiabetic hemodialysis patients and renal transplant recipients. Transplant International, 23(2), 176-181. https://doi.org/10.1111/j.1432-2277.2009.00972.x
Ali, M. E., Abdel-Hafez, H. Z., Mahran, A. M., Mohamed, H. Z., Mohamed, E. R., El-Shazly, A. M., Gadallah, A. M., & Abbas, M. A. (2005). Erectile dysfunction in chronic renal failure patients undergoing hemodialysis in Egypt. International Journal of Impotence Research, 17(2), 180-185. https://doi.org/10.1038/sj.ijir.3901286
Antonucci, M., Palermo, G., Recupero, S. M., Bientinesi, R., Presicce, F., Foschi, N., Bassi, P. F., & Gulino, G. (2016). Male sexual dysfunction in patients with chronic end-stage renal insufficiency and in renal transplant recipients. Archivio Italiano di Urologia e Andrologia, 87(4), 299-305. https://doi.org/10.4081/aiua.2015.4.299
Daker-White, G. (2002). Reliable and valid self-report outcome measures in sexual (dys)function: A systematic review. Archives of Sexual Behavior, 31(2), 197-209. https://doi.org/10.1023/a:1014743304566
Edey, M. M. (2017). Male sexual dysfunction and chronic kidney disease. Frontiers in Medicine, 4, 32. https://doi.org/10.3389/fmed.2017.00032
Esen, B., Kahvecioglu, S., Atay, A. E., Ozgen, G., Okumus, M. M., Seyahi, N., Sit, D., & Kadioglu, P. (2015). Evaluation of relationship between sexual functions, depression and quality of life in patients with chronic kidney disease at predialysis stage. Renal Failure, 37(2), 262-267. https://doi.org/10.3109/0886022X.2014.990348
Fiuk, J. V., & Tadros, N. N. (2019). Erectile dysfunction in renal failure and transplant patients. Translational Andrology and Urology, 8(2), 155-163. https://doi.org/10.21037/tau.2018.09.04
Kang, J., Tian, J., Lu, Y., Song, Y., & Liu, X. (2020). Erectile function after kidney transplantation: A meta-analysis. Translational Andrology and Urology, 9(5), 1967-1979. https://doi.org/10.21037/tau-20-604
Lau, L. C., Adaikan, P. G., Vathsala, A., Srilatha, B., Wong, M. L., Tan, C. S., Deng, X., Sran, H. K., Koh, L. H., & Ma, V. (2018). Clinical prevalence and associated factors of erectile dysfunction in patients undergoing haemodialysis. Annals of the Academy of Medicine, Singapore, 47(2), 78-81.
Mirone, V., Longo, N., Fusco, F., Verze, P., Creta, M., Parazzini, F., & Imbimbo, C. (2009). Renal transplantation does not improve erectile function in hemodialysed patients. European Urology, 56(6), 1047-1053. https://doi.org/10.1016/j.eururo.2008.09.020
Miyata, Y., Shindo, K., Matsuya, F., Noguchi, M., Nishikido, M., Koga, S., & Kanetake, H. (2004). Erectile dysfunction in hemodialysis patients with diabetes mellitus: Association with age and hemoglobin A1c levels. International Journal of Urology, 11(7), 530-534. https://doi.org/10.1111/j.1442-2042.2004.00838.x
Nassir, A. (2009). Sexual function in male patients undergoing treatment for renal failure: A prospective view. The Journal of Sexual Medicine, 6(12), 3407-3414. https://doi.org/10.1111/j.1743-6109.2009.01411.x
Palmer, B. F. (1999). Sexual dysfunction in uremia. Journal of the American Society of Nephrology, 10(6), 1381-1388.
Rosas, S. E., Joffe, M., Franklin, E., Strom, B. L., Kotzker, W., Brensinger, C., Grossman, E., Glasser, D., & Feldman, H. I. (2001). Prevalence and determinants of erectile dysfunction in hemodialysis patients. Kidney International, 59(6), 2259-2266. https://doi.org/10.1046/j.1523-1755.2001.00742.x
Shamloul, R., & Ghanem, H. (2013). Erectile dysfunction. Lancet, 381(9861), 153-165. https://doi.org/10.1016/S0140-6736(12)60520-0
Sooriyamoorthy, T., & Leslie, S. W. (2021). Erectile dysfunction. In StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK562253/
Tavallaii, S. A., Mirzamani, M., Heshmatzade Behzadi, A., Assari, S., Khoddami Vishteh, H. R., Hajarizadeh, B., & Einollahi, B. (2009). Sexual function: A comparison between male renal transplant recipients and hemodialysis patients. The Journal of Sexual Medicine, 6(1), 142-148. https://doi.org/10.1111/j.1743-6109.2008.01047.x