Effects of Essential Oils and Some Constituents from Ingredients of Anti-Cellulite Herbal Compress on 3T3-L1 Adipocytes and Rat Aortae.
Thai herbal compress
adipogenesis
cellulite
essential oil
lipolysis
monoterpenes
vasorelaxation
Journal
Pharmaceuticals (Basel, Switzerland)
ISSN: 1424-8247
Titre abrégé: Pharmaceuticals (Basel)
Pays: Switzerland
ID NLM: 101238453
Informations de publication
Date de publication:
11 Mar 2021
11 Mar 2021
Historique:
received:
21
02
2021
revised:
06
03
2021
accepted:
09
03
2021
entrez:
3
4
2021
pubmed:
4
4
2021
medline:
4
4
2021
Statut:
epublish
Résumé
Cellulite is associated with a complex array of adipocytes under the skin and vascular system. A herbal compress that was previously developed was proven to have an anti-cellulite effect in healthy volunteers within 2 weeks of treatment. However, its mechanism and ingredients responsible for reducing cellulite were not known. The purpose of this study was to investigate the activity of eight essential oils in, and two water extracts from, the ingredients of the herbal compress together with nine monoterpenoid constituents on the 3T3-L1 adipocytes. The vasodilatory effect on rat aortae was also studied. The adipocytes were induced by dexamethasone, 3-isobutyl-1-methylxanthine and insulin. At all concentrations tested, all essential oils, water extracts and their monoterpenoid constituents significantly inhibited lipid accumulation activity (
Identifiants
pubmed: 33799756
pii: ph14030253
doi: 10.3390/ph14030253
pmc: PMC7999046
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Royal Golden Jubilee (RGJ) Ph.D. Programme
ID : 0008/2560
Organisme : Thailand Center of Excellence for Life Sciences
ID : TC-A2/62
Organisme : National Research Council of Thailand
ID : DBG6080005, IRN61W0005
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