Cerebral Expression of Metabotropic Glutamate Receptor Subtype 5 in Idiopathic Autism Spectrum Disorder and Fragile X Syndrome: A Pilot Study.


Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
11 Mar 2021
Historique:
received: 31 01 2021
revised: 26 02 2021
accepted: 04 03 2021
entrez: 3 4 2021
pubmed: 4 4 2021
medline: 4 5 2021
Statut: epublish

Résumé

Multiple lines of evidence suggest that dysfunction of the metabotropic glutamate receptor subtype 5 (mGluR

Identifiants

pubmed: 33799851
pii: ijms22062863
doi: 10.3390/ijms22062863
pmc: PMC7999711
pii:
doi:

Substances chimiques

Receptor, Metabotropic Glutamate 5 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NICHD NIH HHS
ID : P50 HD103538
Pays : United States
Organisme : Radiology BRidge/Development Funding Initiative to STimulate and Advance Research (RAD BriteStar Bridge) Award from the Johns Hopkins University School of Medicine, Baltimore, Maryland
ID : 80046104
Organisme : NCATS NIH HHS
ID : UL1 TR003098
Pays : United States
Organisme : NIH HHS
ID : U54 HD07912
Pays : United States

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Auteurs

James Robert Brašić (JR)

Section of High Resolution Brain Positron Emission Tomography Imaging, Division of Nuclear Medicine and Molecular Imaging, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

Ayon Nandi (A)

Section of High Resolution Brain Positron Emission Tomography Imaging, Division of Nuclear Medicine and Molecular Imaging, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

David S Russell (DS)

Institute for Neurodegenerative Disorders, New Haven, CT 06510, USA.
Research Clinic, Invicro, New Haven, CT 06510, USA.

Danna Jennings (D)

Institute for Neurodegenerative Disorders, New Haven, CT 06510, USA.
Research Clinic, Invicro, New Haven, CT 06510, USA.
Denali Therapeutics, Inc., South San Francisco, CA 94080, USA.

Olivier Barret (O)

Institute for Neurodegenerative Disorders, New Haven, CT 06510, USA.
Research Clinic, Invicro, New Haven, CT 06510, USA.
Laboratoire des Maladies Neurodégénératives, Molecular Imaging Research Center (MIRCen), Institut de Biologie François Jacob, Centre National de la Recherche Scientifique (CNRS), Commissariat à l'Énergie Atomique et aux Énergies Alternatives (CEA), Université Paris-Saclay, 92265 Fontenay-aux-Roses CEDEX, France.

Samuel D Martin (SD)

Section of High Resolution Brain Positron Emission Tomography Imaging, Division of Nuclear Medicine and Molecular Imaging, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Department of Neuroscience, Zanvyl Krieger School of Arts and Sciences, The Johns Hopkins University, Baltimore, MD 21218, USA.

Keith Slifer (K)

Department of Psychiatry and Behavioral Sciences-Child Psychiatry, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Department of Behavioral Psychology, Kennedy Krieger Institute, Baltimore, MD 21205, USA.

Thomas Sedlak (T)

Section of High Resolution Brain Positron Emission Tomography Imaging, Division of Nuclear Medicine and Molecular Imaging, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Department of Psychiatry and Behavioral Sciences-General Psychiatry, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

John P Seibyl (JP)

Institute for Neurodegenerative Disorders, New Haven, CT 06510, USA.
Research Clinic, Invicro, New Haven, CT 06510, USA.

Dean F Wong (DF)

Section of High Resolution Brain Positron Emission Tomography Imaging, Division of Nuclear Medicine and Molecular Imaging, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Laboratory of Central Nervous System (CNS) Neuropsychopharmacology and Multimodal Imaging (CNAMI), Mallinckrodt Institute of Radiology, Washington University, Saint Louis, MO 63110, USA.

Dejan B Budimirovic (DB)

Department of Psychiatry and Behavioral Sciences-Child Psychiatry, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Department of Psychiatry, Kennedy Krieger Institute, Baltimore, MD 21205, USA.

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