Effect-Directed Profiling of 17 Different Fortified Plant Extracts by High-Performance Thin-Layer Chromatography Combined with Six Planar Assays and High-Resolution Mass Spectrometry.
antibacterial assay
bioassay
botanicals
effect-directed analysis
enzyme inhibition assay
health food
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
08 Mar 2021
08 Mar 2021
Historique:
received:
23
01
2021
revised:
21
02
2021
accepted:
22
02
2021
entrez:
3
4
2021
pubmed:
4
4
2021
medline:
14
5
2021
Statut:
epublish
Résumé
An effect-directed profiling method was developed to investigate 17 different fortified plant extracts for potential benefits. Six planar effect-directed assays were piezoelectrically sprayed on the samples separated side-by-side by high-performance thin-layer chromatography. Multipotent compounds with antibacterial, α-glucosidase, β-glucosidase, AChE, tyrosinase and/or β-glucuronidase-inhibiting effects were detected in most fortified plant extracts. A comparatively high level of antimicrobial activity was observed for
Identifiants
pubmed: 33800407
pii: molecules26051468
doi: 10.3390/molecules26051468
pmc: PMC7962818
pii:
doi:
Substances chimiques
Anti-Bacterial Agents
0
Enzyme Inhibitors
0
Plant Extracts
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Deutsche Forschungsgemeinschaft
ID : INST 162/471-1 FUGG
Organisme : Deutsche Forschungsgemeinschaft
ID : INST 162/536-1 FUGG
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