Performance of the EWGSOP2 Cut-Points of Low Grip Strength for Identifying Sarcopenia and Frailty Phenotype: A Cross-Sectional Study in Older Inpatients.
clinical frailty scale
cut-off value
fried phenotype
gait speed
geriatric
muscle strength
post-acute care
rehabilitation
Journal
International journal of environmental research and public health
ISSN: 1660-4601
Titre abrégé: Int J Environ Res Public Health
Pays: Switzerland
ID NLM: 101238455
Informations de publication
Date de publication:
28 03 2021
28 03 2021
Historique:
received:
30
01
2021
revised:
22
03
2021
accepted:
24
03
2021
entrez:
3
4
2021
pubmed:
4
4
2021
medline:
28
4
2021
Statut:
epublish
Résumé
The European Working Group on Sarcopenia has recently proposed revised cut-off values for the definition of low grip strength (EWGSOP2). We therefore compared performance of the EWGSOP2 cut-off definition of low grip strength with other internationally used cut-off points in a sample of older patients. We analyzed geriatric assessment data in a cross-sectional sample of 98 older patients admitted to a post-acute care hospital. First, we compared prevalence of sarcopenia and frailty phenotype in our sample using low grip strength cut-points from the EWGSOP2 and seven other internationally used consensus statements. Second, we calculated correlations between low grip strength and two independent surrogate outcomes (i.e., gait speed, and the clinical frailty scale) for the EWGSOP2 and the other seven cut-point definitions. Prevalence of sarcopenia based on the EWGSOP2 grip strength cut-off values was significantly lower (10.2%) than five of the seven other cut-point definitions (e.g., 19.4% based on Sarcopenia Definitions and Outcomes Consortium (SDOC) criteria). Similarly, frailty phenotype prevalence was significantly lower based on EWGSOP2 cut-points (57.1%) as compared to SDOC (70.4%). The correlation coefficient of gait speed with low grip strength based on EWGSOP2 cut-points was lower (0.145) as compared to other criteria (e.g., SDOC 0.240). Sarcopenia and frailty phenotype were identified considerably less using the EWGSOP2 cut-points for low grip strength, potentially underestimating prevalence of sarcopenia and frailty phenotype in post-acute hospital patients.
Sections du résumé
BACKGROUND
The European Working Group on Sarcopenia has recently proposed revised cut-off values for the definition of low grip strength (EWGSOP2). We therefore compared performance of the EWGSOP2 cut-off definition of low grip strength with other internationally used cut-off points in a sample of older patients.
METHODS
We analyzed geriatric assessment data in a cross-sectional sample of 98 older patients admitted to a post-acute care hospital. First, we compared prevalence of sarcopenia and frailty phenotype in our sample using low grip strength cut-points from the EWGSOP2 and seven other internationally used consensus statements. Second, we calculated correlations between low grip strength and two independent surrogate outcomes (i.e., gait speed, and the clinical frailty scale) for the EWGSOP2 and the other seven cut-point definitions.
RESULTS
Prevalence of sarcopenia based on the EWGSOP2 grip strength cut-off values was significantly lower (10.2%) than five of the seven other cut-point definitions (e.g., 19.4% based on Sarcopenia Definitions and Outcomes Consortium (SDOC) criteria). Similarly, frailty phenotype prevalence was significantly lower based on EWGSOP2 cut-points (57.1%) as compared to SDOC (70.4%). The correlation coefficient of gait speed with low grip strength based on EWGSOP2 cut-points was lower (0.145) as compared to other criteria (e.g., SDOC 0.240).
CONCLUSIONS
Sarcopenia and frailty phenotype were identified considerably less using the EWGSOP2 cut-points for low grip strength, potentially underestimating prevalence of sarcopenia and frailty phenotype in post-acute hospital patients.
Identifiants
pubmed: 33800552
pii: ijerph18073498
doi: 10.3390/ijerph18073498
pmc: PMC8037004
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Références
J Nutr Health Aging. 2020;24(1):125-126
pubmed: 31886819
J Gerontol A Biol Sci Med Sci. 2014 May;69(5):559-66
pubmed: 24737558
CMAJ. 2005 Aug 30;173(5):489-95
pubmed: 16129869
J Appl Physiol (1985). 2003 Nov;95(5):1851-60
pubmed: 14555665
BMC Geriatr. 2017 Oct 16;17(1):238
pubmed: 29037155
Age Ageing. 2010 Jul;39(4):412-23
pubmed: 20392703
BMC Geriatr. 2020 Oct 7;20(1):393
pubmed: 33028215
Chest. 2020 Jul;158(1S):S12-S20
pubmed: 32658647
J Am Geriatr Soc. 2020 Jul;68(7):1438-1444
pubmed: 32633830
PLoS One. 2014 Dec 04;9(12):e113637
pubmed: 25474696
In Vivo. 2017 Sep-Oct;31(5):917-924
pubmed: 28882959
J Am Geriatr Soc. 2020 Jul;68(7):1429-1437
pubmed: 32633824
J Am Med Dir Assoc. 2020 Mar;21(3):300-307.e2
pubmed: 32033882
Lancet. 2013 Mar 2;381(9868):752-62
pubmed: 23395245
J Am Geriatr Soc. 2020 Jul;68(7):1410-1418
pubmed: 32150289
Arch Gerontol Geriatr. 2020 Sep - Oct;90:104125
pubmed: 32534364
Arch Gerontol Geriatr. 2012 Sep-Oct;55(2):e9-13
pubmed: 22795189
BMC Geriatr. 2019 Apr 27;19(1):120
pubmed: 31029082
J Cachexia Sarcopenia Muscle. 2014 Dec;5(4):253-9
pubmed: 25425503
J Gerontol A Biol Sci Med Sci. 2014 May;69(5):547-58
pubmed: 24737557
Eur J Clin Nutr. 2021 Apr;75(4):653-660
pubmed: 33060812
Arch Phys Med Rehabil. 2019 Mar;100(3):509-513
pubmed: 30092204
Age Ageing. 2019 Jan 1;48(1):16-31
pubmed: 30312372
PLoS One. 2020 Jun 1;15(6):e0234200
pubmed: 32479543
J Gerontol A Biol Sci Med Sci. 2001 Mar;56(3):M146-56
pubmed: 11253156
Arch Gerontol Geriatr. 2017 Sep;72:164-168
pubmed: 28667843
Age Ageing. 2019 Sep 1;48(5):719-724
pubmed: 31112221
J Am Geriatr Soc. 2020 Jul;68(7):1419-1428
pubmed: 32633834