Effect of Training-Detraining Phases of Multicomponent Exercises and BCAA Supplementation on Inflammatory Markers and Albumin Levels in Frail Older Persons.
Aged
Aged, 80 and over
Aging
/ physiology
Amino Acids, Branched-Chain
/ administration & dosage
Biomarkers
/ blood
Cognition
/ physiology
Cognitive Dysfunction
/ prevention & control
Cytokines
/ blood
Dietary Supplements
Exercise Therapy
/ methods
Female
Frail Elderly
Frailty
/ prevention & control
Geriatric Assessment
Humans
Male
Muscle Strength
/ physiology
Peroxidase
/ blood
Pragmatic Clinical Trials as Topic
Prospective Studies
Quality of Life
Serum Albumin
/ metabolism
cognitive impairment
cytokines
inflammaging
physical frailty
protein intake
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
28 Mar 2021
28 Mar 2021
Historique:
received:
28
02
2021
revised:
19
03
2021
accepted:
21
03
2021
entrez:
3
4
2021
pubmed:
4
4
2021
medline:
5
5
2021
Statut:
epublish
Résumé
Nowadays, it is accepted that the regular practice of exercise and branched-chain amino acids supplementation (BCAAs) can benefit the immune responses in older persons, prevent the occurrence of physical frailty (PF), cognitive decline, and aging-related comorbidities. However, the impact of their combination (as non-pharmacological interventions) in albumin and the inflammatory markers is not fully understood. Therefore, we investigated the effect of a 40-week multifactorial intervention [MIP, multicomponent exercise (ME) associated or not with BCAAs] on plasma levels of inflammatory markers and albumin in frail older persons (≥75 years old) living at residential care homes (RCH). This study consisted of a prospective, naturalistic, controlled clinical trial with four arms of multifactorial and experimental (interventions-wahshout-interventions) design. The intervention groups were ME + BCAAs (
Identifiants
pubmed: 33800577
pii: nu13041106
doi: 10.3390/nu13041106
pmc: PMC8066027
pii:
doi:
Substances chimiques
Amino Acids, Branched-Chain
0
Biomarkers
0
Cytokines
0
Serum Albumin
0
Peroxidase
EC 1.11.1.7
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
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