The Roles of Membrane Technology in Artificial Organs: Current Challenges and Perspectives.

artificial kidney artificial liver artificial lung artificial organs bioartificial pancreas biocompatibility membrane

Journal

Membranes
ISSN: 2077-0375
Titre abrégé: Membranes (Basel)
Pays: Switzerland
ID NLM: 101577807

Informations de publication

Date de publication:
28 Mar 2021
Historique:
received: 01 03 2021
revised: 20 03 2021
accepted: 20 03 2021
entrez: 3 4 2021
pubmed: 4 4 2021
medline: 4 4 2021
Statut: epublish

Résumé

The recent outbreak of the COVID-19 pandemic in 2020 reasserted the necessity of artificial lung membrane technology to treat patients with acute lung failure. In addition, the aging world population inevitably leads to higher demand for better artificial organ (AO) devices. Membrane technology is the central component in many of the AO devices including lung, kidney, liver and pancreas. Although AO technology has improved significantly in the past few decades, the quality of life of organ failure patients is still poor and the technology must be improved further. Most of the current AO literature focuses on the treatment and the clinical use of AO, while the research on the membrane development aspect of AO is relatively scarce. One of the speculated reasons is the wide interdisciplinary spectrum of AO technology, ranging from biotechnology to polymer chemistry and process engineering. In this review, in order to facilitate the membrane aspects of the AO research, the roles of membrane technology in the AO devices, along with the current challenges, are summarized. This review shows that there is a clear need for better membranes in terms of biocompatibility, permselectivity, module design, and process configuration.

Identifiants

pubmed: 33800659
pii: membranes11040239
doi: 10.3390/membranes11040239
pmc: PMC8065507
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Subventions

Organisme : Incheon National University
ID : Research Assistance Program 2020

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Auteurs

Bao Tran Duy Nguyen (BT)

Department of Energy and Chemical Engineering, Incheon National University, Incheon 22012, Korea.

Hai Yen Nguyen Thi (HY)

Department of Energy and Chemical Engineering, Incheon National University, Incheon 22012, Korea.

Bich Phuong Nguyen Thi (BP)

Department of Energy and Chemical Engineering, Incheon National University, Incheon 22012, Korea.

Dong-Ku Kang (DK)

Department of Chemistry, Incheon National University, Incheon 22012, Korea.

Jeong F Kim (JF)

Department of Energy and Chemical Engineering, Incheon National University, Incheon 22012, Korea.
Innovation Center for Chemical Engineering, Incheon National University, Incheon 22012, Korea.

Classifications MeSH