Secondary ARDS Following Acute Pancreatitis: Is Extracorporeal Membrane Oxygenation Feasible or Futile?

acute respiratory distress syndrome (ARDS) extra corporeal life support (ECLS) extra corporeal membrane oxygenation (ECMO) pancreatitis

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
02 Mar 2021
Historique:
received: 08 01 2021
revised: 04 02 2021
accepted: 24 02 2021
entrez: 3 4 2021
pubmed: 4 4 2021
medline: 4 4 2021
Statut: epublish

Résumé

To assess the feasibility of extracorporeal membrane oxygenation (ECMO) or life support (ECLS) as last resort life support therapy in patients with acute pancreatitis and subsequent secondary acute respiratory distress syndrome (ARDS). Retrospective analysis from January 2013, to April 2020, of ECMO patients with pancreatitis-induced ARDS at a German University Hospital. Demographics, hospital and ICU length of stay, duration of ECMO therapy, days on mechanical ventilation, fluid balance, need for decompressive laparotomy, amount of blood products, prognostic scores (CCI (Charlson Comorbidity Index), SOFA (Sequential Organ Failure Assessment), RESP(Respiratory ECMO Survival Prediction), SAVE (Survival after Veno-Arterial ECMO)), and the total known length of survival were assessed. A total of ECLS can be performed as a rescue therapy in patients with pancreatitis and secondary ARDS, but nevertheless mortality remains still high. Thus, this last-resort therapy may be best suited for patients with fewer pre-existing comorbidities and no other organ failure.

Identifiants

pubmed: 33801239
pii: jcm10051000
doi: 10.3390/jcm10051000
pmc: PMC7958117
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Mathias Schmandt (M)

Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, 53127 Bonn, Germany.

Tim R Glowka (TR)

Department of Surgery, University Hospital Bonn, 53127 Bonn, Germany.

Stefan Kreyer (S)

Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, 53127 Bonn, Germany.

Thomas Muders (T)

Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, 53127 Bonn, Germany.

Stefan Muenster (S)

Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, 53127 Bonn, Germany.

Nils Ulrich Theuerkauf (NU)

Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, 53127 Bonn, Germany.

Jörg C Kalff (JC)

Department of Surgery, University Hospital Bonn, 53127 Bonn, Germany.

Christian Putensen (C)

Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, 53127 Bonn, Germany.

Jens-Christian Schewe (JC)

Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, 53127 Bonn, Germany.

Stefan Felix Ehrentraut (SF)

Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, 53127 Bonn, Germany.

Classifications MeSH