Coordinated Expression of HPV-6 Genes with Predominant E4 and E5 Expression in Laryngeal Papilloma.
anti-E4 monoclonal antibody
human papillomavirus 6
laryngeal papilloma
long-term alteration of viral load
viral lineage
viral mRNA expression
Journal
Microorganisms
ISSN: 2076-2607
Titre abrégé: Microorganisms
Pays: Switzerland
ID NLM: 101625893
Informations de publication
Date de publication:
03 Mar 2021
03 Mar 2021
Historique:
received:
14
02
2021
revised:
26
02
2021
accepted:
27
02
2021
entrez:
3
4
2021
pubmed:
4
4
2021
medline:
4
4
2021
Statut:
epublish
Résumé
Laryngeal papilloma (LP) associated with human papillomavirus (HPV)-6 or -11 infection shows aggressive growth. However, the detailed molecular mechanism of virus-driven tumorigenesis has not been uncovered fully. HPV-6 viral gene expression and dynamic alterations were investigated with in situ localization of viral DNA and RNA in 13 patients with HPV-6-infected laryngeal papilloma. The average viral load was 4.80 × 10
Identifiants
pubmed: 33802595
pii: microorganisms9030520
doi: 10.3390/microorganisms9030520
pmc: PMC7998961
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Grants-in-Aid for Early-Career Scientists (JSPS KAKENHI）
ID : 18K16896
Organisme : the Construction of the Okinawa Science & Technology Innovation System
ID : 20E1000035
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