Holmium-Containing Bioactive Glasses Dispersed in Poloxamer 407 Hydrogel as a Theragenerative Composite for Bone Cancer Treatment.
bioactive glass
bone cancer
brachytherapy
holmium
hydrogel
theragenerative biomaterial
Journal
Materials (Basel, Switzerland)
ISSN: 1996-1944
Titre abrégé: Materials (Basel)
Pays: Switzerland
ID NLM: 101555929
Informations de publication
Date de publication:
17 Mar 2021
17 Mar 2021
Historique:
received:
30
01
2021
revised:
26
02
2021
accepted:
05
03
2021
entrez:
3
4
2021
pubmed:
4
4
2021
medline:
4
4
2021
Statut:
epublish
Résumé
Holmium-containing bioactive glasses can be applied in bone cancer treatment because the holmium content can be neutron activated, having suitable properties for brachytherapy applications, while the bioactive glass matrix can regenerate the bone alterations induced by the tumor. To facilitate the application of these glasses in clinical practice, we proposed a composite based on Poloxamer 407 thermoresponsive hydrogel, with suitable properties for applications as injectable systems. Therefore, in this work, we evaluated the influence of holmium-containing glass particles on the properties of Poloxamer 407 hydrogel (20
Identifiants
pubmed: 33802678
pii: ma14061459
doi: 10.3390/ma14061459
pmc: PMC8002559
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Fundação de Amparo à Pesquisa do Estado de São Paulo
ID : 2016/16512-9
Organisme : Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
ID : 002
Organisme : Conselho Nacional de Desenvolvimento Científico e Tecnológico
ID : 307718/2019-0
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