Clinical Observation of Allergic Conjunctival Diseases with Portable and Recordable Slit-Lamp Device.
allergic conjunctivital diseases
conventional slit-lamp microscope
portable
recordable
smart eye camera
Journal
Diagnostics (Basel, Switzerland)
ISSN: 2075-4418
Titre abrégé: Diagnostics (Basel)
Pays: Switzerland
ID NLM: 101658402
Informations de publication
Date de publication:
17 Mar 2021
17 Mar 2021
Historique:
received:
25
02
2021
revised:
15
03
2021
accepted:
15
03
2021
entrez:
3
4
2021
pubmed:
4
4
2021
medline:
4
4
2021
Statut:
epublish
Résumé
The incidence of allergic conjunctival diseases (ACDs) is gradually increasing worldwide. Both ophthalmologists and non-ophthalmologists prescribe eye drops to treat ACDs; however, there are many cases which are treated without sufficient examination and diagnosis of the eyes. We have invented a portable, recordable, and smartphone-attachable slit-lamp device-Smart Eye Camera (SEC). The purpose of this study was to compare the diagnostic abilities of ACDs between the SEC and the conventional, non-portable slit-lamp microscope. This prospective observational study included 32 eyes of 17 Japanese patients (mean age: 21.5 ± 14.8 years; range: 11-51 years; female: 5). The severity of 10 objective signs in the palpebral conjunctiva, bulbar conjunctiva, limbus, and cornea were scored on a grading scale of 0 to 4 (0 = normal; 1+ = mild; 2+ = moderate; 3+ = severe), respectively. First, the conventional slit-lamp microscope was used to examine the grade of the ACDs. Second, another ophthalmologist filmed the eyes using the SEC and two other ophthalmologists evaluated the grades on another day. The correlation and inter-rater reproducibility in total scores among the two devices were determined. Total scores of clinical signs, evaluated by the two approaches, correlated significantly (both eyes: r = 0.918 (95% CI: 0.839 to 0.959; The SEC is as reliable as the conventional non-portable slit-lamp microscope for assessing ACDs.
Sections du résumé
BACKGROUND
BACKGROUND
The incidence of allergic conjunctival diseases (ACDs) is gradually increasing worldwide. Both ophthalmologists and non-ophthalmologists prescribe eye drops to treat ACDs; however, there are many cases which are treated without sufficient examination and diagnosis of the eyes. We have invented a portable, recordable, and smartphone-attachable slit-lamp device-Smart Eye Camera (SEC). The purpose of this study was to compare the diagnostic abilities of ACDs between the SEC and the conventional, non-portable slit-lamp microscope.
METHODS
METHODS
This prospective observational study included 32 eyes of 17 Japanese patients (mean age: 21.5 ± 14.8 years; range: 11-51 years; female: 5). The severity of 10 objective signs in the palpebral conjunctiva, bulbar conjunctiva, limbus, and cornea were scored on a grading scale of 0 to 4 (0 = normal; 1+ = mild; 2+ = moderate; 3+ = severe), respectively. First, the conventional slit-lamp microscope was used to examine the grade of the ACDs. Second, another ophthalmologist filmed the eyes using the SEC and two other ophthalmologists evaluated the grades on another day. The correlation and inter-rater reproducibility in total scores among the two devices were determined.
RESULTS
RESULTS
Total scores of clinical signs, evaluated by the two approaches, correlated significantly (both eyes: r = 0.918 (95% CI: 0.839 to 0.959;
CONCLUSIONS
CONCLUSIONS
The SEC is as reliable as the conventional non-portable slit-lamp microscope for assessing ACDs.
Identifiants
pubmed: 33802736
pii: diagnostics11030535
doi: 10.3390/diagnostics11030535
pmc: PMC8002473
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Casio Science Promotion Foundation
ID : 38-40
Références
Pediatr Allergy Immunol. 2014 Jun;25(4):314-22
pubmed: 24438133
Skin Res Technol. 2001 May;7(2):73-7
pubmed: 11393207
Allergol Int. 2011 Mar;60(2):171-89
pubmed: 21636965
Postgrad Med J. 2001 Oct;77(912):654-5
pubmed: 11571373
Immunol Allergy Clin North Am. 2008 Feb;28(1):83-103, vi
pubmed: 18282547
Sci Rep. 2019 Dec 3;9(1):18205
pubmed: 31796815
Ann Allergy Asthma Immunol. 2019 Apr;122(4):387-392.e1
pubmed: 30639466
Arch Immunol Ther Exp (Warsz). 2007 May-Jun;55(3):173-7
pubmed: 17557145
Ann Acad Med Singap. 2016 Jan;45(1):6-11
pubmed: 27118223
Allergol Int. 2017 Apr;66(2):220-229
pubmed: 28209324
Sensors (Basel). 2021 Feb 19;21(4):
pubmed: 33669487
Cont Lens Anterior Eye. 2016 Feb;39(1):80-1
pubmed: 26440291
Eur J Ophthalmol. 2010 Jan-Feb;20(1):1-11
pubmed: 19882521
Allergol Int. 2006 Sep;55(3):301-3
pubmed: 17075271
Sci Total Environ. 2014 Jul 15;487:493-9
pubmed: 24802272
Clin Case Rep. 2019 Aug 20;7(10):2004-2005
pubmed: 31624627
Ophthalmologe. 2017 Jun;114(6):514-524
pubmed: 28283768
Diagnostics (Basel). 2020 Aug 09;10(8):
pubmed: 32784828
Br J Ophthalmol. 2014 Aug;98(8):1023-7
pubmed: 24695688
Eur J Ophthalmol. 2018 Jul;28(4):372-377
pubmed: 29554813
J Allergy Clin Immunol. 2016 Aug;138(2):459-467.e2
pubmed: 26964692
Allergy Asthma Proc. 2013 Jan-Feb;34(1):33-41
pubmed: 23406935
Clin Exp Immunol. 2008 Sep;153 Suppl 1:17-21
pubmed: 18721324
Acta Ophthalmol. 2009 Mar;87(2):133-47
pubmed: 18786127
Ann Allergy Asthma Immunol. 2003 Sep;91(3):288-96
pubmed: 14533662
PLoS One. 2019 May 9;14(5):e0215130
pubmed: 31071120
Cornea. 2014 Nov;33 Suppl 11:S13-8
pubmed: 25289719
Singapore Med J. 2016 Sep;57(9):507-10
pubmed: 26768065
Allergol Int. 2020 Jul;69(3):346-355
pubmed: 33211650
Allergy Asthma Clin Immunol. 2021 Feb 1;17(1):11
pubmed: 33522964
Rev Alerg Mex. 2007 Mar-Apr;54(2):41-53
pubmed: 17542245