Polysaccharides-Based Complex Particles' Protective Role on the Stability and Bioactivity of Immobilized Curcumin.
Adsorption
Animals
Antioxidants
/ analysis
Biphenyl Compounds
/ chemistry
Buffers
Cattle
Curcumin
/ chemistry
Flavonoids
/ analysis
Free Radical Scavengers
/ chemistry
Hydrogen-Ion Concentration
Inhibitory Concentration 50
Ions
Metals
/ chemistry
Phenols
/ analysis
Picrates
/ chemistry
Polysaccharides
/ chemistry
Protective Agents
/ pharmacology
Serum Albumin, Bovine
/ chemistry
Solutions
Spectroscopy, Fourier Transform Infrared
Ultraviolet Rays
BSA adsorption
antioxidant activity
curcumin metal complexes
immobilized curcumin
pH and light stability
polymeric matrix
polysaccharides particles
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
17 Mar 2021
17 Mar 2021
Historique:
received:
16
02
2021
revised:
12
03
2021
accepted:
13
03
2021
entrez:
3
4
2021
pubmed:
4
4
2021
medline:
23
4
2021
Statut:
epublish
Résumé
The curcumin degradation represents a significant limitation for its applications. The stability of free curcumin (FC) and immobilized curcumin in complex particles (ComPs) based on different polysaccharides was studied under the action of several factors. Ultraviolet-visible (UV-VIS) and Fourier-transform infrared (FTIR) spectroscopy proved the FC photodegradation and its role as a metal chelator: 82% of FC and between 26% and 39.79% of curcumin within the ComPs degraded after exposure for 28 days to natural light. The degradation half-life (t
Identifiants
pubmed: 33802882
pii: ijms22063075
doi: 10.3390/ijms22063075
pmc: PMC8002829
pii:
doi:
Substances chimiques
Antioxidants
0
Biphenyl Compounds
0
Buffers
0
Flavonoids
0
Free Radical Scavengers
0
Ions
0
Metals
0
Phenols
0
Picrates
0
Polysaccharides
0
Protective Agents
0
Solutions
0
Serum Albumin, Bovine
27432CM55Q
1,1-diphenyl-2-picrylhydrazyl
DFD3H4VGDH
Curcumin
IT942ZTH98
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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