Aspirin and Statin Use and the Risk of Gallbladder Cancer.

aspirin cancer prevention gallbladder cancer statin

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
09 Mar 2021
Historique:
received: 02 02 2021
revised: 26 02 2021
accepted: 03 03 2021
entrez: 3 4 2021
pubmed: 4 4 2021
medline: 4 4 2021
Statut: epublish

Résumé

Aspirin and statin drugs have been associated with reduced risk of several gastrointestinal cancers, but their association with gallbladder cancer (GBC) has not been well established. We evaluated the association of aspirin and statins with the risk of GBC. Patients with GBC managed at Mayo Clinic between 2000 and 2019 were matched 1:2 with a general patient pool by age and sex. Univariable and multivariable logistic regression models were used to assess associations between GBC and aspirin or statin use. The analysis included 795 cases and 1590 controls, with a median age of 67 years. Aspirin or statin use alone or in combination was higher in controls (

Identifiants

pubmed: 33803387
pii: cancers13051186
doi: 10.3390/cancers13051186
pmc: PMC7967123
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : The Mayo Clinic Center for Clinical and Translational Science
ID : UL TR000135

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Auteurs

Kritika Prasai (K)

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55902, USA.

Sri Harsha Tella (SH)

Department of Oncology, Mayo Clinic, Rochester, MN 55902, USA.

Siddhartha Yadav (S)

Department of Oncology, Mayo Clinic, Rochester, MN 55902, USA.

Anuhya Kommalapati (A)

Department of Oncology, Mayo Clinic, Rochester, MN 55902, USA.

Kristin Mara (K)

Department of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN 55902, USA.

Mohamed Mady (M)

Department of Oncology, Mayo Clinic, Rochester, MN 55902, USA.

Mohamed A Hassan (MA)

Department of Internal Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15260, USA.

Nicha Wongjarupong (N)

Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.

Natalia Rodriguez-Payan (N)

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55902, USA.

Mitesh Borad (M)

Department of Oncology, Mayo Clinic, Scottsdale, AZ 85259, USA.

Tushar Patel (T)

Division of Transplantation, Mayo Clinic, Jacksonville, FL 32224, USA.

Lewis R Roberts (LR)

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55902, USA.

Amit Mahipal (A)

Department of Oncology, Mayo Clinic, Rochester, MN 55902, USA.

Classifications MeSH